PDB entry 1v1k

View 1v1k on RCSB PDB site
Description: cdk2 in complex with a disubstituted 4, 6-bis anilino pyrimidine cdk4 inhibitor
Class: transferase
Keywords: serine/threonine-protein kinase, mitosis, transferase
Deposited on 2004-04-16, released 2004-05-04
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 2.31 Å
R-factor: 0.211
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1V1K
    • Uniprot P24941 (0-297)
    Domains in SCOPe 2.07: d1v1ka_
  • Heterogens: 3FP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1v1kA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >1v1kA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirltaireisllkelnhpnivklldv
    ihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlk
    pqnllintegaikladfglarvvtlwyrapeillgckyystavdiwslgcifaemvtrra
    lfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrs
    llsqmlhydpnkrisakaalahpffqdvtkpvphlrl