PDB entry 1uxu

View 1uxu on RCSB PDB site
Description: Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax
Class: oxidoreductase
Keywords: gapn, aldh, amp, glyceraldehyde 3-phosphate, glycolysis, regulation, catalysis, oxidoreductase
Deposited on 2004-03-01, released 2004-08-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glyceraldehyde-3-phosphate dehydrogenase (nadp+)
    Species: Thermoproteus tenax [TaxId:2271]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O57693 (Start-500)
      • engineered mutation (377)
      • conflict (401)
    Domains in SCOPe 2.08: d1uxua_
  • Heterogens: NAP, AMP, G3H, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1uxuA (A:)
mragllegvikekggvpvypsylagewggsgqeievkspidlatiakvispsreevertl
dvlfkrgrwsardmpgterlavlrkaadiiernldvfaevlvmnagkpksaavgevkaav
drlrlaeldlkkiggdyipgdwtydtleteglvrreplgvvaaitpfnyplfdavnkity
sfiygnavvvkpsisdplpaamavkalldagfppdaiallnlpgkeaekivaddrvaavs
ftgstevgervvkvggvkqyvmelgggdpaivledadldlaadkiargiysyagqrcdai
klvlaerpvygklveevakrlsslrvgdprdptvdvgplispsavdemmaaiedavekgg
rvlaggrrlgptyvqptfveapadrvkdmvlykrevfapvalavevkdldqaielangrp
ygldaavfgrdvvkirravrllevgaiyindmprhgigyypfggrkksgvfregigyave
avtayktivfnykgkgvwkye

    Sequence, based on observed residues (ATOM records): (download) 
    >1uxuA (A:)
agllegvikekggvpvypsylagewggsgqeievkspidlatiakvispsreevertldv
lfkrgrwsardmpgterlavlrkaadiiernldvfaevlvmnagkpksaavgevkaavdr
lrlaeldlkkiggdyipgdwtydtleteglvrreplgvvaaitpfnyplfdavnkitysf
iygnavvvkpsisdplpaamavkalldagfppdaiallnlpgkeaekivaddrvaavsft
gstevgervvkvggvkqyvmelgggdpaivledadldlaadkiargiysyagqrcdaikl
vlaerpvygklveevakrlsslrvgdprdptvdvgplispsavdemmaaiedavekggrv
laggrrlgptyvqptfveapadrvkdmvlykrevfapvalavevkdldqaielangrpyg
ldaavfgrdvvkirravrllevgaiyindmprhgigyypfggrkksgvfregigyaveav
tayktivfnykgkgvwkye