PDB entry 1uxg

View 1uxg on RCSB PDB site
Description: Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface.
Class: oxidoreductase
Keywords: oxidoreductase, tricarboxylic acid cycle, malate dehydrogenase
Deposited on 2004-02-25, released 2004-08-26
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-04-15, with a file datestamp of 2015-04-10.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: malate dehydrogenase
    Species: Chloroflexus aurantiacus [TaxId:1108]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1uxga1, d1uxga2
  • Chain 'B':
    Compound: malate dehydrogenase
    Species: Chloroflexus aurantiacus [TaxId:1108]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1uxgb1, d1uxgb2
  • Heterogens: NAD, FUM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1uxgA (A:)
mrkkisiigagfvgsttahwlaakelgdivlldivegvpqgkaldlyeaspiegfdvrvt
gtnnyadtansdvivvtsgaprkpgmsredlikvnaditracisqaaplspnaviimvnn
pldamtylaaevsgfpkervigqagvldaaryrtfiameagvsvedvqamlmgghgdemv
plprfstisgipvsefiapdrlaqivertrkgggeivnllktgsayyapaaataqmveav
lkdkkrvmpvaayltgqyglndiyfgvpvilgaggvekilelplneeemallnasakavr
atldtlksl

    Sequence, based on observed residues (ATOM records): (download) 
    >1uxgA (A:)
rkkisiigagfvgsttahwlaakelgdivlldivegvpqgkaldlyeaspiegfdvrvtg
tnnyadtansdvivvtsgaprkpgmsredlikvnaditracisqaaplspnaviimvnnp
ldamtylaaevsgfpkervigqagvldaaryrtfiameagvsvedvqamlmgghgdemvp
lprfstisgipvsefiapdrlaqivertrkgggeivnllktgsayyapaaataqmveavl
kdkkrvmpvaayltgqyglndiyfgvpvilgaggvekilelplneeemallnasakavra
tldtlksl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1uxgB (B:)
mrkkisiigagfvgsttahwlaakelgdivlldivegvpqgkaldlyeaspiegfdvrvt
gtnnyadtansdvivvtsgaprkpgmsredlikvnaditracisqaaplspnaviimvnn
pldamtylaaevsgfpkervigqagvldaaryrtfiameagvsvedvqamlmgghgdemv
plprfstisgipvsefiapdrlaqivertrkgggeivnllktgsayyapaaataqmveav
lkdkkrvmpvaayltgqyglndiyfgvpvilgaggvekilelplneeemallnasakavr
atldtlksl

    Sequence, based on observed residues (ATOM records): (download) 
    >1uxgB (B:)
rkkisiigagfvgsttahwlaakelgdivlldivegvpqgkaldlyeaspiegfdvrvtg
tnnyadtansdvivvtsgaprkpgmsredlikvnaditracisqaaplspnaviimvnnp
ldamtylaaevsgfpkervigqagvldaaryrtfiameagvsvedvqamlmgghgdemvp
lprfstisgipvsefiapdrlaqivertrkgggeivnllktgsayyapaaataqmveavl
kdkkrvmpvaayltgqyglndiyfgvpvilgaggvekilelplneeemallnasakavra
tldtlksl