PDB entry 1uwl

View 1uwl on RCSB PDB site
Description: 1.76A Structure of Urocanate Hydratase from Pseudomonas putida
Class: hydrolase
Keywords: hydrolase, urocanase, imidazolonepropionate, histidine metabolism, lyase
Deposited on 2004-02-05, released 2004-08-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 1.76 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Urocanate hydratase
    Species: Pseudomonas putida [TaxId:303]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P25080
      • engineered mutation (197)
      • conflict (5)
      • conflict (163-164)
      • conflict (166)
    Domains in SCOPe 2.08: d1uwla_
  • Chain 'B':
    Compound: Urocanate hydratase
    Species: Pseudomonas putida [TaxId:303]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P25080
      • engineered mutation (197)
      • conflict (5)
      • conflict (163-164)
      • conflict (166)
    Domains in SCOPe 2.08: d1uwlb_
  • Heterogens: NAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1uwlA (A:)
    mtdnnnyrdveiraprgnkltakswlteaplrmlmnnldpqvaenpkelvvyggigraar
    nwecydkivetltrleddetllvqsgkpvgvfkthsnaprvliansnlvphwanwehfne
    ldakglamygqmtagswiyigsqgivqgtyetfveagrqhyggslkgkwvltaglggmgg
    aqplaatlagacslniesqqsridfrletryvdeqatdlddalvriakytaegkaisial
    hgnaaeilpelvkrgvrpdmvtdqtsahdplngylpagwtweqyrdraqtepaavvkaak
    qsmavhvqamldfqkqgvptfdygnnirqmakeegvanafdfpgfvpayirplfcrgvgp
    frwaalsgeaediyktdakvkelipddahlhrwldmarerisfqglparicwvglglrak
    lglafnemvrsgelsapvvigrdhldsgsvsspnreteamrdgsdavsdwpllnallnta
    ggatwvslhhgggvgmgfsqhsgmvivcdgtdeaaeriarvltndpgtgvmrhadagydi
    aidcakeqgldlpmitg
    

    Sequence, based on observed residues (ATOM records): (download)
    >1uwlA (A:)
    nnyrdveiraprgnkltakswlteaplrmlmnnldpqvaenpkelvvyggigraarnwec
    ydkivetltrleddetllvqsgkpvgvfkthsnaprvliansnlvphwanwehfneldak
    glamygqmtagswiyigsqgivqgtyetfveagrqhyggslkgkwvltaglggmggaqpl
    aatlagacslniesqqsridfrletryvdeqatdlddalvriakytaegkaisialhgna
    aeilpelvkrgvrpdmvtdqtsahdplngylpagwtweqyrdraqtepaavvkaakqsma
    vhvqamldfqkqgvptfdygnnirqmakeegvanafdfpgfvpayirplfcrgvgpfrwa
    alsgeaediyktdakvkelipddahlhrwldmarerisfqglparicwvglglraklgla
    fnemvrsgelsapvvigrdhldsgsvsspnreteamrdgsdavsdwpllnallntaggat
    wvslhhgggvgmgfsqhsgmvivcdgtdeaaeriarvltndpgtgvmrhadagydiaidc
    akeqgldlpmi
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1uwlB (B:)
    mtdnnnyrdveiraprgnkltakswlteaplrmlmnnldpqvaenpkelvvyggigraar
    nwecydkivetltrleddetllvqsgkpvgvfkthsnaprvliansnlvphwanwehfne
    ldakglamygqmtagswiyigsqgivqgtyetfveagrqhyggslkgkwvltaglggmgg
    aqplaatlagacslniesqqsridfrletryvdeqatdlddalvriakytaegkaisial
    hgnaaeilpelvkrgvrpdmvtdqtsahdplngylpagwtweqyrdraqtepaavvkaak
    qsmavhvqamldfqkqgvptfdygnnirqmakeegvanafdfpgfvpayirplfcrgvgp
    frwaalsgeaediyktdakvkelipddahlhrwldmarerisfqglparicwvglglrak
    lglafnemvrsgelsapvvigrdhldsgsvsspnreteamrdgsdavsdwpllnallnta
    ggatwvslhhgggvgmgfsqhsgmvivcdgtdeaaeriarvltndpgtgvmrhadagydi
    aidcakeqgldlpmitg
    

    Sequence, based on observed residues (ATOM records): (download)
    >1uwlB (B:)
    nnyrdveiraprgnkltakswlteaplrmlmnnldpqvaenpkelvvyggigraarnwec
    ydkivetltrleddetllvqsgkpvgvfkthsnaprvliansnlvphwanwehfneldak
    glamygqmtagswiyigsqgivqgtyetfveagrqhyggslkgkwvltaglggmggaqpl
    aatlagacslniesqqsridfrletryvdeqatdlddalvriakytaegkaisialhgna
    aeilpelvkrgvrpdmvtdqtsahdplngylpagwtweqyrdraqtepaavvkaakqsma
    vhvqamldfqkqgvptfdygnnirqmakeegvanafdfpgfvpayirplfcrgvgpfrwa
    alsgeaediyktdakvkelipddahlhrwldmarerisfqglparicwvglglraklgla
    fnemvrsgelsapvvigrdhldsgsvsspnreteamrdgsdavsdwpllnallntaggat
    wvslhhgggvgmgfsqhsgmvivcdgtdeaaeriarvltndpgtgvmrhadagydiaidc
    akeqgldlpm