PDB entry 1uvr

View 1uvr on RCSB PDB site
Description: structure of human pdk1 kinase domain in complex with bim-8
Class: transferase
Keywords: protein kinase, pkb, pdk1, inhibitor, ly333531, bisindolyl maleimide, bim-8, diabetes, cancer, transferase
Deposited on 2004-01-22, released 2004-03-04
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.81 Å
R-factor: 0.17642
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-phosphoinositide dependent protein kinase-1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1uvra_
  • Heterogens: GOL, SO4, BI8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1uvrA (A:)
    ppqprkkrpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtre
    rdvmsrldhpffvklyftfqddeklyfglsyakngellkyirkigsfdetctrfytaeiv
    saleylhgkgiihrdlkpenillnedmhiqitdfgtakvlspeskqaransfvgtaqyvs
    pellteksackssdlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkar
    dlvekllvldatkrlgceemegygplkahpffesvtwenlhqqtppklt
    

    Sequence, based on observed residues (ATOM records): (download)
    >1uvrA (A:)
    ppqprkkrpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtre
    rdvmsrldhpffvklyftfqddeklyfglsyakngellkyirkigsfdetctrfytaeiv
    saleylhgkgiihrdlkpenillnedmhiqitdfgtakvlsparansfvgtaqyvspell
    teksackssdlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkardlve
    kllvldatkrlgceemegygplkahpffesvtwenlhqqtppklt