PDB entry 1uum

View 1uum on RCSB PDB site
Description: rat dihydroorotate dehydrogenase (dhod)in complex with atovaquone
Class: oxidoreductase
Keywords: dihydroorotate dehydrogenase, brequinar, atovaquone, nucleotide metabolism, pyrimidine biosynthesis, fad, oxidoreductase, flavoprotein, transit peptide
Deposited on 2004-01-06, released 2004-04-01
The last revision prior to the SCOP 1.73 freeze date was dated 2004-04-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.216
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydroorotate dehydrogenase
    Species: RATTUS RATTUS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1uuma_
  • Chain 'B':
    Compound: dihydroorotate dehydrogenase
    Species: RATTUS RATTUS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1uumb_
  • Heterogens: BOG, FMN, ORO, AFI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1uumA (A:)
hhhhhhatgddhfyaeylmpglqrlldpesahrlavrvtslgllpratfqdsdmlevkvl
ghkfrnpvgiaagfdkngeavdglyklgfgfvevgsvtpqpqegnprprvfrlpedqavi
nrygfnshglsvvehrlrarqqkqaqltadglplginlgknktsedaaadyaegvrtlgp
ladylvvnvsspntaglrslqgktelrhllskvlqerdalkgtrkpavlvkiapdltaqd
kediasvarelgidglivtnttvsrpvglqgalrsetgglsgkplrdlstqtiremyalt
qgripiigvggvssgqdalekiqagaslvqlytaliflgppvvvrvkreleallkergft
tvtdaigadhrr

    Sequence, based on observed residues (ATOM records): (download) 
    >1uumA (A:)
yaeylmpglqrlldpesahrlavrvtslgllpratfqdsdmlevkvlghkfrnpvgiaag
fdkngeavdglyklgfgfvevgsvtpqpqegnprprvfrlpedqavinrygfnshglsvv
ehrlrarqqkqaqltadglplginlgknktsedaaadyaegvrtlgpladylvvnvssqg
ktelrhllskvlqerdalkgtrkpavlvkiapdltaqdkediasvarelgidglivtntt
vsrpvglqgalrsetgglsgkplrdlstqtiremyaltqgripiigvggvssgqdaleki
qagaslvqlytaliflgppvvvrvkreleallkergfttvtdaigadhrr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1uumB (B:)
hhhhhhatgddhfyaeylmpglqrlldpesahrlavrvtslgllpratfqdsdmlevkvl
ghkfrnpvgiaagfdkngeavdglyklgfgfvevgsvtpqpqegnprprvfrlpedqavi
nrygfnshglsvvehrlrarqqkqaqltadglplginlgknktsedaaadyaegvrtlgp
ladylvvnvsspntaglrslqgktelrhllskvlqerdalkgtrkpavlvkiapdltaqd
kediasvarelgidglivtnttvsrpvglqgalrsetgglsgkplrdlstqtiremyalt
qgripiigvggvssgqdalekiqagaslvqlytaliflgppvvvrvkreleallkergft
tvtdaigadhrr

    Sequence, based on observed residues (ATOM records): (download) 
    >1uumB (B:)
yaeylmpglqrlldpesahrlavrvtslgllpratfqdsdmlevkvlghkfrnpvgiaag
fdkngeavdglyklgfgfvevgsvtpqpqegnprprvfrlpedqavinrygfnshglsvv
ehrlrarqqkqaqltadglplginlgknktsedaaadyaegvrtlgpladylvvnvssqg
ktelrhllskvlqerdalkgtrkpavlvkiapdltaqdkediasvarelgidglivtntt
vsrpvglqgalrsetgglsgkplrdlstqtiremyaltqgripiigvggvssgqdaleki
qagaslvqlytaliflgppvvvrvkreleallkergfttvtdaigadhrr