PDB entry 1uu3

View 1uu3 on RCSB PDB site
Description: structure of human pdk1 kinase domain in complex with ly333531
Class: transferase
Keywords: protein kinase, pkb, pdk1, inhibitor, ly333531, diabetes, cancer, transferase, serine/threonine-protein kinase
Deposited on 2003-12-15, released 2004-03-04
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.174
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-phosphoinositide dependent protein kinase-1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1uu3a_
  • Heterogens: GOL, SO4, LY4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1uu3A (A:)
mdgtaaeprpgagslqhaqpppqprkkrpedfkfgkilgegsfstvvlarelatsreyai
kilekrhiikenkvpyvtrerdvmsrldhpffvklyftfqddeklyfglsyakngellky
irkigsfdetctrfytaeivsaleylhgkgiihrdlkpenillnedmhiqitdfgtakvl
speskqaransfvgtaqyvspellteksackssdlwalgciiyqlvaglppfragneyli
fqkiikleydfpekffpkardlvekllvldatkrlgceemegygplkahpffesvtwenl
hqqtppklta

    Sequence, based on observed residues (ATOM records): (download) 
    >1uu3A (A:)
qprkkrpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtrerd
vmsrldhpffvklyftfqddeklyfglsyakngellkyirkigsfdetctrfytaeivsa
leylhgkgiihrdlkpenillnedmhiqitdfgtakvlsfvgtaqyvspellteksacks
sdlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkardlvekllvldat
krlgceemegygplkahpffesvtwenlhqqtppklta