PDB entry 1uu3

View 1uu3 on RCSB PDB site
Description: structure of human pdk1 kinase domain in complex with ly333531
Class: transferase
Keywords: protein kinase, pkb, pdk1, inhibitor, ly333531, diabetes, cancer, transferase, serine/threonine-protein kinase
Deposited on 2003-12-15, released 2004-03-04
The last revision prior to the SCOP 1.75 freeze date was dated 2004-03-04, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.174
AEROSPACI score: 0.7 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-phosphoinositide dependent protein kinase-1
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1uu3a_
  • Heterogens: SO4, LY4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1uu3A (A:)
mdgtaaeprpgagslqhaqpppqprkkrpedfkfgkilgegsfstvvlarelatsreyai
kilekrhiikenkvpyvtrerdvmsrldhpffvklyftfqddeklyfglsyakngellky
irkigsfdetctrfytaeivsaleylhgkgiihrdlkpenillnedmhiqitdfgtakvl
speskqaransfvgtaqyvspellteksackssdlwalgciiyqlvaglppfragneyli
fqkiikleydfpekffpkardlvekllvldatkrlgceemegygplkahpffesvtwenl
hqqtppklta

    Sequence, based on observed residues (ATOM records): (download) 
    >1uu3A (A:)
qprkkrpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtrerd
vmsrldhpffvklyftfqddeklyfglsyakngellkyirkigsfdetctrfytaeivsa
leylhgkgiihrdlkpenillnedmhiqitdfgtakvlsfvgtaqyvspellteksacks
sdlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkardlvekllvldat
krlgceemegygplkahpffesvtwenlhqqtppklta