PDB entry 1uu3

View 1uu3 on RCSB PDB site
Description: Structure of human PDK1 kinase domain in complex with LY333531
Class: transferase
Keywords: protein kinase, pkb, pdk1, inhibitor, ly333531, diabetes, cancer, transferase, serine/threonine-protein kinase
Deposited on 2003-12-15, released 2004-03-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-04-24, with a file datestamp of 2019-04-19.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-phosphoinositide dependent protein kinase-1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1uu3a_
  • Heterogens: GOL, SO4, LY4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1uu3A (A:)
    mdgtaaeprpgagslqhaqpppqprkkrpedfkfgkilgegsfstvvlarelatsreyai
    kilekrhiikenkvpyvtrerdvmsrldhpffvklyftfqddeklyfglsyakngellky
    irkigsfdetctrfytaeivsaleylhgkgiihrdlkpenillnedmhiqitdfgtakvl
    speskqaransfvgtaqyvspellteksackssdlwalgciiyqlvaglppfragneyli
    fqkiikleydfpekffpkardlvekllvldatkrlgceemegygplkahpffesvtwenl
    hqqtppklta
    

    Sequence, based on observed residues (ATOM records): (download)
    >1uu3A (A:)
    qprkkrpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtrerd
    vmsrldhpffvklyftfqddeklyfglsyakngellkyirkigsfdetctrfytaeivsa
    leylhgkgiihrdlkpenillnedmhiqitdfgtakvlsfvgtaqyvspellteksacks
    sdlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkardlvekllvldat
    krlgceemegygplkahpffesvtwenlhqqtppklta