PDB entry 1umy

View 1umy on RCSB PDB site
Description: BHMT from rat liver
Class: transferase
Keywords: transferase, methionine synthesis, homocysteine metabolism, betaine, methyltransferase, zinc
Deposited on 2003-09-02, released 2004-05-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-12-05, with a file datestamp of 2018-11-30.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Betaine--homocysteine S-methyltransferase 1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: BHMT
    Database cross-references and differences (RAF-indexed):
    • Uniprot O09171
      • conflict (246-247)
    Domains in SCOPe 2.08: d1umya_
  • Chain 'B':
    Compound: Betaine--homocysteine S-methyltransferase 1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: BHMT
    Database cross-references and differences (RAF-indexed):
    • Uniprot O09171
      • conflict (246-247)
    Domains in SCOPe 2.08: d1umyb_
  • Chain 'C':
    Compound: Betaine--homocysteine S-methyltransferase 1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: BHMT
    Database cross-references and differences (RAF-indexed):
    • Uniprot O09171
      • conflict (246-247)
    Domains in SCOPe 2.08: d1umyc_
  • Chain 'D':
    Compound: Betaine--homocysteine S-methyltransferase 1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: BHMT
    Database cross-references and differences (RAF-indexed):
    • Uniprot O09171
      • conflict (246-247)
    Domains in SCOPe 2.08: d1umyd_
  • Heterogens: ZN, BME, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1umyA (A:)
mapiagkkakrgilerlnagevvigdggfvfalekrgyvkagpwtpeaavehpeavrqlh
reflragsnvmqtftfyasedklenrgnyvaekisgqkvneaacdiarqvadegdalvag
gvsqtpsylscksetevkkifhqqlevfmkknvdfliaeyfehveeavwavealktsgkp
iaatmcigpegdlhgvspgecavrlvkagaaivgvnchfdpstslqtiklmkegleaarl
kaylmsqplayhtpdcgkqgfidlpefpfgleprvatrwdiqkyareaynlgvryiggcc
gfepyhiraiaeelapergflppasekhgswgsgldmhtkpwirararkeywqnlriasg
rpynpsmskpdawgvtkgaaelmqqkeatteqqlralfekqkfksaq

    Sequence, based on observed residues (ATOM records): (download) 
    >1umyA (A:)
krgilerlnagevvigdggfvfalekrgyvkagpwtpeaavehpeavrqlhreflragsn
vmqtftfyassgqkvneaacdiarqvadegdalvaggvsqtpsylscksetevkkifhqq
levfmkknvdfliaeyfehveeavwavealktsgkpiaatmcigpegdlhgvspgecavr
lvkagaaivgvnchfdpstslqtiklmkegleaarlkaylmsqplayhtpdcgkqgfidl
pefpfgleprvatrwdiqkyareaynlgvryiggccgfepyhiraiaeelapergflppa
sekhgswgsgldmhtkpwirararkeywqnlriasgrpynpsmskpdawgvtkgaaelmq
qkeatteqqlralfe

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1umyB (B:)
mapiagkkakrgilerlnagevvigdggfvfalekrgyvkagpwtpeaavehpeavrqlh
reflragsnvmqtftfyasedklenrgnyvaekisgqkvneaacdiarqvadegdalvag
gvsqtpsylscksetevkkifhqqlevfmkknvdfliaeyfehveeavwavealktsgkp
iaatmcigpegdlhgvspgecavrlvkagaaivgvnchfdpstslqtiklmkegleaarl
kaylmsqplayhtpdcgkqgfidlpefpfgleprvatrwdiqkyareaynlgvryiggcc
gfepyhiraiaeelapergflppasekhgswgsgldmhtkpwirararkeywqnlriasg
rpynpsmskpdawgvtkgaaelmqqkeatteqqlralfekqkfksaq

    Sequence, based on observed residues (ATOM records): (download) 
    >1umyB (B:)
krgilerlnagevvigdggfvfalekrgyvkagpwtpeaavehpeavrqlhreflragsn
vmqtftfyasedaekisgqkvneaacdiarqvadegdalvaggvsqtpsylscksetevk
kifhqqlevfmkknvdfliaeyfehveeavwavealktsgkpiaatmcigpegdlhgvsp
gecavrlvkagaaivgvnchfdpstslqtiklmkegleaarlkaylmsqplayhtpdcgk
qgfidlpefpfgleprvatrwdiqkyareaynlgvryiggccgfepyhiraiaeelaper
gflppasekhgswgsgldmhtkpwirararkeywqnlriasgrpynpsmskpdawgvtkg
aaelmqqkeatteqqlralfe

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1umyC (C:)
mapiagkkakrgilerlnagevvigdggfvfalekrgyvkagpwtpeaavehpeavrqlh
reflragsnvmqtftfyasedklenrgnyvaekisgqkvneaacdiarqvadegdalvag
gvsqtpsylscksetevkkifhqqlevfmkknvdfliaeyfehveeavwavealktsgkp
iaatmcigpegdlhgvspgecavrlvkagaaivgvnchfdpstslqtiklmkegleaarl
kaylmsqplayhtpdcgkqgfidlpefpfgleprvatrwdiqkyareaynlgvryiggcc
gfepyhiraiaeelapergflppasekhgswgsgldmhtkpwirararkeywqnlriasg
rpynpsmskpdawgvtkgaaelmqqkeatteqqlralfekqkfksaq

    Sequence, based on observed residues (ATOM records): (download) 
    >1umyC (C:)
krgilerlnagevvigdggfvfalekrgyvkagpwtpeaavehpeavrqlhreflragsn
vmqtftfyasgqkvneaacdiarqvadegdalvaggvsqtpsylscksetevkkifhqql
evfmkknvdfliaeyfehveeavwavealktsgkpiaatmcigpegdlhgvspgecavrl
vkagaaivgvnchfdpstslqtiklmkegleaarlkaylmsqplayhtpdcgkqgfidlp
efpfgleprvatrwdiqkyareaynlgvryiggccgfepyhiraiaeelapergflppas
ekhgswgsgldmhtkpwirararkeywqnlriasgrpynpsmskpdawgvtkgaaelmqq
keatteqqlralfekqkfksa

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1umyD (D:)
mapiagkkakrgilerlnagevvigdggfvfalekrgyvkagpwtpeaavehpeavrqlh
reflragsnvmqtftfyasedklenrgnyvaekisgqkvneaacdiarqvadegdalvag
gvsqtpsylscksetevkkifhqqlevfmkknvdfliaeyfehveeavwavealktsgkp
iaatmcigpegdlhgvspgecavrlvkagaaivgvnchfdpstslqtiklmkegleaarl
kaylmsqplayhtpdcgkqgfidlpefpfgleprvatrwdiqkyareaynlgvryiggcc
gfepyhiraiaeelapergflppasekhgswgsgldmhtkpwirararkeywqnlriasg
rpynpsmskpdawgvtkgaaelmqqkeatteqqlralfekqkfksaq

    Sequence, based on observed residues (ATOM records): (download) 
    >1umyD (D:)
krgilerlnagevvigdggfvfalekrgyvkagpwtpeaavehpeavrqlhreflragsn
vmqtftfyakisgqkvneaacdiarqvadegdalvaggvsqtpsylscksetevkkifhq
qlevfmkknvdfliaeyfehveeavwavealktsgkpiaatmcigpegdlhgvspgecav
rlvkagaaivgvnchfdpstslqtiklmkegleaarlkaylmsqplayhtpdcgkqgfid
lpefpfgleprvatrwdiqkyareaynlgvryiggccgfepyhiraiaeelapergflpp
asekhgswgsgldmhtkpwirararkeywqnlriasgrpynpsmskpdawgvtkgaaelm
qqkeatteqqlralfekqkfks