PDB entry 1ump

View 1ump on RCSB PDB site
Description: geometry of triterpene conversion to pentacarbocyclic hopene
Class: isomerase
Keywords: isomerase, triterpene cyclase, cholesterol biosynthesis, oxidosqualene cyclase, monotopic membrane protein
Deposited on 2003-08-27, released 2004-02-03
The last revision prior to the SCOP 1.73 freeze date was dated 2004-02-03, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.13 Å
R-factor: 0.18691
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: squalene--hopene cyclase
    Species: Alicyclobacillus acidocaldarius
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1umpa1, d1umpa2
  • Chain 'B':
    Compound: squalene--hopene cyclase
    Species: Alicyclobacillus acidocaldarius
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1umpb1, d1umpb2
  • Chain 'C':
    Compound: squalene--hopene cyclase
    Species: Alicyclobacillus acidocaldarius
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1umpc1, d1umpc2
  • Heterogens: C8E, SQA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1umpA (A:)
maeqlveapayartldraveyllscqkdegywwgpllsnvtmeaeyvllchildrvdrdr
mekirryllheqredgtwalypggppdldttieayvalkyigmsrdeepmqkalrfiqsq
ggiessrvftrmwlalvgeypwekvpmvppeimflgkrmplniyefgswaratvvalsiv
msrqpvfplperarvpelyetdvpprrrgakggggwifdaldralhgyqklsvhpfrraa
eiraldwllerqagdgswggiqppwfyalialkildmtqhpafikgweglelygveldyg
gwmfqasispvwdtglavlalraaglpadhdrlvkagewlldrqitvpgdwavkrpnlkp
ggfafqfdnvyypdvddtavvvwalntlrlpderrrrdamtkgfrwivgmqssnggwgay
dvdntsdlpnhipfcdfgevtdppsedvtahvlecfgsfgyddawkvirraveylkreqk
pdgswfgrwgvnylygtgavvsalkavgidtrepyiqkaldwveqhqnpdggwgedcrsy
edpayagkgastpsqtawalmaliaggraeseaarrgvqylvetqrpdggwdepyytgtg
fpgdfylgytmyrhvfptlalgrykqaierr

    Sequence, based on observed residues (ATOM records): (download) 
    >1umpA (A:)
ayartldraveyllscqkdegywwgpllsnvtmeaeyvllchildrvdrdrmekirryll
heqredgtwalypggppdldttieayvalkyigmsrdeepmqkalrfiqsqggiessrvf
trmwlalvgeypwekvpmvppeimflgkrmplniyefgswaratvvalsivmsrqpvfpl
perarvpelyetdvpprrrgakggggwifdaldralhgyqklsvhpfrraaeiraldwll
erqagdgswggiqppwfyalialkildmtqhpafikgweglelygveldyggwmfqasis
pvwdtglavlalraaglpadhdrlvkagewlldrqitvpgdwavkrpnlkpggfafqfdn
vyypdvddtavvvwalntlrlpderrrrdamtkgfrwivgmqssnggwgaydvdntsdlp
nhipfcdfgevtdppsedvtahvlecfgsfgyddawkvirraveylkreqkpdgswfgrw
gvnylygtgavvsalkavgidtrepyiqkaldwveqhqnpdggwgedcrsyedpayagkg
astpsqtawalmaliaggraeseaarrgvqylvetqrpdggwdepyytgtgfpgdfylgy
tmyrhvfptlalgrykqaie

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1umpB (B:)
maeqlveapayartldraveyllscqkdegywwgpllsnvtmeaeyvllchildrvdrdr
mekirryllheqredgtwalypggppdldttieayvalkyigmsrdeepmqkalrfiqsq
ggiessrvftrmwlalvgeypwekvpmvppeimflgkrmplniyefgswaratvvalsiv
msrqpvfplperarvpelyetdvpprrrgakggggwifdaldralhgyqklsvhpfrraa
eiraldwllerqagdgswggiqppwfyalialkildmtqhpafikgweglelygveldyg
gwmfqasispvwdtglavlalraaglpadhdrlvkagewlldrqitvpgdwavkrpnlkp
ggfafqfdnvyypdvddtavvvwalntlrlpderrrrdamtkgfrwivgmqssnggwgay
dvdntsdlpnhipfcdfgevtdppsedvtahvlecfgsfgyddawkvirraveylkreqk
pdgswfgrwgvnylygtgavvsalkavgidtrepyiqkaldwveqhqnpdggwgedcrsy
edpayagkgastpsqtawalmaliaggraeseaarrgvqylvetqrpdggwdepyytgtg
fpgdfylgytmyrhvfptlalgrykqaierr

    Sequence, based on observed residues (ATOM records): (download) 
    >1umpB (B:)
ayartldraveyllscqkdegywwgpllsnvtmeaeyvllchildrvdrdrmekirryll
heqredgtwalypggppdldttieayvalkyigmsrdeepmqkalrfiqsqggiessrvf
trmwlalvgeypwekvpmvppeimflgkrmplniyefgswaratvvalsivmsrqpvfpl
perarvpelyetdvpprrrgakggggwifdaldralhgyqklsvhpfrraaeiraldwll
erqagdgswggiqppwfyalialkildmtqhpafikgweglelygveldyggwmfqasis
pvwdtglavlalraaglpadhdrlvkagewlldrqitvpgdwavkrpnlkpggfafqfdn
vyypdvddtavvvwalntlrlpderrrrdamtkgfrwivgmqssnggwgaydvdntsdlp
nhipfcdfgevtdppsedvtahvlecfgsfgyddawkvirraveylkreqkpdgswfgrw
gvnylygtgavvsalkavgidtrepyiqkaldwveqhqnpdggwgedcrsyedpayagkg
astpsqtawalmaliaggraeseaarrgvqylvetqrpdggwdepyytgtgfpgdfylgy
tmyrhvfptlalgrykqaie

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1umpC (C:)
maeqlveapayartldraveyllscqkdegywwgpllsnvtmeaeyvllchildrvdrdr
mekirryllheqredgtwalypggppdldttieayvalkyigmsrdeepmqkalrfiqsq
ggiessrvftrmwlalvgeypwekvpmvppeimflgkrmplniyefgswaratvvalsiv
msrqpvfplperarvpelyetdvpprrrgakggggwifdaldralhgyqklsvhpfrraa
eiraldwllerqagdgswggiqppwfyalialkildmtqhpafikgweglelygveldyg
gwmfqasispvwdtglavlalraaglpadhdrlvkagewlldrqitvpgdwavkrpnlkp
ggfafqfdnvyypdvddtavvvwalntlrlpderrrrdamtkgfrwivgmqssnggwgay
dvdntsdlpnhipfcdfgevtdppsedvtahvlecfgsfgyddawkvirraveylkreqk
pdgswfgrwgvnylygtgavvsalkavgidtrepyiqkaldwveqhqnpdggwgedcrsy
edpayagkgastpsqtawalmaliaggraeseaarrgvqylvetqrpdggwdepyytgtg
fpgdfylgytmyrhvfptlalgrykqaierr

    Sequence, based on observed residues (ATOM records): (download) 
    >1umpC (C:)
ayartldraveyllscqkdegywwgpllsnvtmeaeyvllchildrvdrdrmekirryll
heqredgtwalypggppdldttieayvalkyigmsrdeepmqkalrfiqsqggiessrvf
trmwlalvgeypwekvpmvppeimflgkrmplniyefgswaratvvalsivmsrqpvfpl
perarvpelyetdvpprrrgakggggwifdaldralhgyqklsvhpfrraaeiraldwll
erqagdgswggiqppwfyalialkildmtqhpafikgweglelygveldyggwmfqasis
pvwdtglavlalraaglpadhdrlvkagewlldrqitvpgdwavkrpnlkpggfafqfdn
vyypdvddtavvvwalntlrlpderrrrdamtkgfrwivgmqssnggwgaydvdntsdlp
nhipfcdfgevtdppsedvtahvlecfgsfgyddawkvirraveylkreqkpdgswfgrw
gvnylygtgavvsalkavgidtrepyiqkaldwveqhqnpdggwgedcrsyedpayagkg
astpsqtawalmaliaggraeseaarrgvqylvetqrpdggwdepyytgtgfpgdfylgy
tmyrhvfptlalgrykqaie