PDB entry 1uml

View 1uml on RCSB PDB site
Description: Crystal structure of adenosine deaminase complexed with a potent inhibitor FR233624
Class: hydrolase
Keywords: beta barrel, zinc
Deposited on 2003-10-03, released 2004-09-21
The last revision prior to the SCOP 1.73 freeze date was dated 2004-09-21, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.226
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: adenosine deaminase
    Species: BOS TAURUS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56658
      • see remark 999 (6)
      • see remark 999 (30-31)
      • see remark 999 (55)
      • see remark 999 (58)
      • see remark 999 (75)
      • see remark 999 (77)
      • see remark 999 (197)
      • see remark 999 (244)
      • see remark 999 (259)
      • see remark 999 (277)
      • see remark 999 (279)
      • see remark 999 (311-312)
      • see remark 999 (350)
    Domains in SCOP 1.73: d1umla_
  • Heterogens: ZN, FR4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1umlA (A:)
aqtpafdkpkvelhvhldgaikpetilyygkrrgialpadtpeelqniigmdkpltlpdf
lakfdyympaiagcrdaikriayefvemkakdgvvyvevrysphllanskvepipwnqae
gdltpdevvslvnqglqegerdfgvkvrsilccmrhqpswssevvelckkyreqtvvaid
lagdetiegsslfpghvqayaeavksgvhrtvhagevgsanvvkeavdtlkterlghgyh
tledttlynrlrqenmhfeicpwssyltgawkpdtehavirfkndqvnyslntddplifk
stldtdyqmtkkdmgfteeefkrlninaakssflpedekkelldllykayrmpspa

    Sequence, based on observed residues (ATOM records): (download) 
    >1umlA (A:)
tpafdkpkvelhvhldgaikpetilyygkrrgialpadtpeelqniigmdkpltlpdfla
kfdyympaiagcrdaikriayefvemkakdgvvyvevrysphllanskvepipwnqaegd
ltpdevvslvnqglqegerdfgvkvrsilccmrhqpswssevvelckkyreqtvvaidla
gdetiegsslfpghvqayaeavksgvhrtvhagevgsanvvkeavdtlkterlghgyhtl
edttlynrlrqenmhfeicpwssyltgawkpdtehavirfkndqvnyslntddplifkst
ldtdyqmtkkdmgfteeefkrlninaakssflpedekkelldllykayr