PDB entry 1umb

View 1umb on RCSB PDB site
Description: branched-chain 2-oxo acid dehydrogenase (E1) from Thermus thermophilus HB8 in holo-form
Class: Oxidoreductase
Keywords: alpha(2)beta(2) tetramer, structural genomics, RIKEN Structural Genomics/Proteomics Initiative, RSGI
Deposited on 2003-09-25, released 2004-03-30
The last revision prior to the SCOP 1.75 freeze date was dated 2004-03-30, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.169
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-oxo acid dehydrogenase alpha subunit
    Species: Thermus thermophilus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1umba_
  • Chain 'B':
    Compound: 2-oxo acid dehydrogenase beta subunit
    Species: Thermus thermophilus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1umbb1, d1umbb2
  • Chain 'C':
    Compound: 2-oxo acid dehydrogenase alpha subunit
    Species: Thermus thermophilus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1umbc_
  • Chain 'D':
    Compound: 2-oxo acid dehydrogenase beta subunit
    Species: Thermus thermophilus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1umbd1, d1umbd2
  • Heterogens: MG, TDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1umbA (A:)
mvkethrfetfteepirligeegewlgdfpldlegeklrrlyrdmlaarmlderytilir
tgktsfiapaagheaaqvaiahairpgfdwvfpyyrdhglalalgiplkellgqmlatka
dpnkgrqmpehpgskalnfftvaspiashvppaagaaismkllrtgqvavctfgdgatse
gdwyaginfaavqgapavfiaennfyaisvdyrhqthsptiadkahafgipgylvdgmdv
lasyyvvkeaverarrgegpslvelrvyrygphssadddsryrpkeevafwrkkdpiprf
rrflearglwneeweedvreeiraelerglkeaeeagpvppewmfedvfaekpwhllrqe
allkeel

    Sequence, based on observed residues (ATOM records): (download) 
    >1umbA (A:)
hrfetfteepirligeegewlgdfpldlegeklrrlyrdmlaarmlderytilirtgkts
fiapaagheaaqvaiahairpgfdwvfpyyrdhglalalgiplkellgqmlatkadpnkg
rqmpehpgskalnfftvaspiashvppaagaaismkllrtgqvavctfgdgatsegdwya
ginfaavqgapavfiaennfyaisvdyrhqthsptiadkahafgipgylvdgmdvlasyy
vvkeaverarrgegpslvelrvyrygphssadddsryrpkeevafwrkkdpiprfrrfle
arglwneeweedvreeiraelerglkeaeeagpvppewmfedvfaekpwhllrqeallke
el

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1umbB (B:)
malmtmvqalnraldeemakdprvvvlgedvgkrggvflvtegllqkygpdrvmdtplse
aaivgaalgmaahglrpvaeiqfadyifpgfdqlvsqvaklryrsggqftaplvvrmpsg
ggvrgghhhsqspeahfvhtaglkvvavstpydakgllkaairdedpvvflepkrlyrsv
keevpeedytlpigkaalrregkdltlicygtvmpevlqaaaelakagvsaevldlrtlm
pwdyeavmnsvaktgrvvlvsdaprhasfvsevaatiaedlldmllappirvtgfdtpyp
yaqdklylptvtrilnaakraldy

    Sequence, based on observed residues (ATOM records): (download) 
    >1umbB (B:)
almtmvqalnraldeemakdprvvvlgedvgkrggvflvtegllqkygpdrvmdtplsea
aivgaalgmaahglrpvaeiqfadyifpgfdqlvsqvaklryrsggqftaplvvrmpsgg
gvrgghhhsqspeahfvhtaglkvvavstpydakgllkaairdedpvvflepkrlyrsvk
eevpeedytlpigkaalrregkdltlicygtvmpevlqaaaelakagvsaevldlrtlmp
wdyeavmnsvaktgrvvlvsdaprhasfvsevaatiaedlldmllappirvtgfdtpypy
aqdklylptvtrilnaakraldy

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1umbC (C:)
mvkethrfetfteepirligeegewlgdfpldlegeklrrlyrdmlaarmlderytilir
tgktsfiapaagheaaqvaiahairpgfdwvfpyyrdhglalalgiplkellgqmlatka
dpnkgrqmpehpgskalnfftvaspiashvppaagaaismkllrtgqvavctfgdgatse
gdwyaginfaavqgapavfiaennfyaisvdyrhqthsptiadkahafgipgylvdgmdv
lasyyvvkeaverarrgegpslvelrvyrygphssadddsryrpkeevafwrkkdpiprf
rrflearglwneeweedvreeiraelerglkeaeeagpvppewmfedvfaekpwhllrqe
allkeel

    Sequence, based on observed residues (ATOM records): (download) 
    >1umbC (C:)
hrfetfteepirligeegewlgdfpldlegeklrrlyrdmlaarmlderytilirtgkts
fiapaagheaaqvaiahairpgfdwvfpyyrdhglalalgiplkellgqmlatkadpnkg
rqmpehpgskalnfftvaspiashvppaagaaismkllrtgqvavctfgdgatsegdwya
ginfaavqgapavfiaennfyaisvdyrhqthsptiadkahafgipgylvdgmdvlasyy
vvkeaverarrgegpslvelrvyrygphssadddsryrpkeevafwrkkdpiprfrrfle
arglwneeweedvreeiraelerglkeaeeagpvppewmfedvfaekpwhllrqeallke
e

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1umbD (D:)
malmtmvqalnraldeemakdprvvvlgedvgkrggvflvtegllqkygpdrvmdtplse
aaivgaalgmaahglrpvaeiqfadyifpgfdqlvsqvaklryrsggqftaplvvrmpsg
ggvrgghhhsqspeahfvhtaglkvvavstpydakgllkaairdedpvvflepkrlyrsv
keevpeedytlpigkaalrregkdltlicygtvmpevlqaaaelakagvsaevldlrtlm
pwdyeavmnsvaktgrvvlvsdaprhasfvsevaatiaedlldmllappirvtgfdtpyp
yaqdklylptvtrilnaakraldy

    Sequence, based on observed residues (ATOM records): (download) 
    >1umbD (D:)
almtmvqalnraldeemakdprvvvlgedvgkrggvflvtegllqkygpdrvmdtplsea
aivgaalgmaahglrpvaeiqfadyifpgfdqlvsqvaklryrsggqftaplvvrmpsgg
gvrgghhhsqspeahfvhtaglkvvavstpydakgllkaairdedpvvflepkrlyrsvk
eevpeedytlpigkaalrregkdltlicygtvmpevlqaaaelakagvsaevldlrtlmp
wdyeavmnsvaktgrvvlvsdaprhasfvsevaatiaedlldmllappirvtgfdtpypy
aqdklylptvtrilnaakraldy