PDB entry 1uma

View 1uma on RCSB PDB site
Description: alpha-thrombin (hirugen) complexed with na-(n,n-dimethylcarbamoyl)-alpha-azalysine
Class: complex (serine protease/inhibitor)
Keywords: hydrolase, serine protease, kringle, alpha-thrombin, hirugen complex (serine protease/inhibitor)
Deposited on 1996-03-26, released 1996-11-08
The last revision prior to the SCOP 1.75 freeze date was dated 1996-11-08, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.168
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: alpha-thrombin
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1uma.1
  • Chain 'I':
    Compound: hirudin I
    Species: Hirudo medicinalis
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: alpha-thrombin
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1uma.1
  • Heterogens: NAG, IN2, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1umaH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge

    Sequence, based on observed residues (ATOM records): (download) 
    >1umaH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwgqpsvlqvvnlpiverpvckdstriritdnmf
cagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrl
kkwiqkvidqfge

  • Chain 'I':
    No sequence available.

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1umaL (L:)
tfgsgeadcglrplfekksledkterellesyidgr