PDB entry 1u9n

View 1u9n on RCSB PDB site
Description: Crystal structure of the transcriptional regulator EthR in a ligand bound conformation opens therapeutic perspectives against tuberculosis and leprosy
Class: DNA binding protein
Keywords: TetR family, transcriptional repressor, protein-ligand complex, DNA BINDING PROTEIN
Deposited on 2004-08-10, released 2004-11-16
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.201
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transcriptional repressor EthR
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1u9na1, d1u9na2
  • Heterogens: CNS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1u9nA (A:)
    mgsshhhhhhssglvprgshvttsaasqaslprgrrtarpsgddrelailataenlledr
    pladisvddlakgagisrptfyfyfpskeavlltlldrvvnqadmalqtlaenpadtdre
    nmwrtginvffetfgshkavtragqaaratsvevaelwstfmqkwiaytaavidaerdrg
    aaprtlpahelatalnlmnertlfasfageqpsvpearvldtlvhiwvtsiygenr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1u9nA (A:)
    gddrelailataenlledrpladisvddlakgagisrptfyfyfpskeavlltlldrvvn
    qadmalqtlaenpadtdrenmwrtginvffetfgshkavtragqaaratsvevaelwstf
    mqkwiaytaavidaerdrgaaprtlpahelatalnlmnertlfasfageqpsvpearvld
    tlvhiwvtsiygen