PDB entry 1u92
View 1u92 on RCSB PDB site
Description: Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide Analog E-[Dap]-DKWQS (cyclic)
Class: immune system
Keywords: Fab complex, HIV-1 Neutralization, gp41 Peptide, IMMUNE SYSTEM
Deposited on
2004-08-09, released
2004-10-05
The last revision prior to the SCOPe 2.08 freeze date was dated
2010-01-05, with a file datestamp of
2009-12-31.
Experiment type: XRAY
Resolution: 2.24 Å
R-factor: 0.225
AEROSPACI score: 0.34
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: antibody 2f5 (light chain)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1u92a1, d1u92a2 - Chain 'B':
Compound: antibody 2f5 (heavy chain)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1u92b1, d1u92b2 - Chain 'C':
Compound: gp41 peptide analog
Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
Database cross-references and differences (RAF-indexed):
- Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1u92A (A:)
alqltqspsslsasvgdrititcrasqgvtsalawyrqkpgsppqlliydasslesgvps
rfsgsgsgteftltistlrpedfatyycqqlhfyphtfgggtrvdvrrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyecevthqglsspvtksfnrgec
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1u92B (B:)
ritlkesgpplvkptqtltltcsfsgfslsdfgvgvgwirqppgkalewlaiiysdddkr
yspslntrltitkdtsknqvvlvmtrvspvdtatyfcahrrgpttlfgvpiargpvnamd
vwgqgitvtisststkgpsvfplapsskstaggaaalgclvkdyfpepvtvswnsgalts
gvhtfpavlqssglyslssvvtvpssslgtqtytcnvnhkpsntkvdkrvepks
Sequence, based on observed residues (ATOM records): (download)
>1u92B (B:)
ritlkesgpplvkptqtltltcsfsgfslsdfgvgvgwirqppgkalewlaiiysdddkr
yspslntrltitkdtsknqvvlvmtrvspvdtatyfcahrrgpttlfgvpiargpvnamd
vwgqgitvtisststkgpsvfplapaaalgclvkdyfpepvtvswnsgaltsgvhtfpav
lqssglyslssvvtvpssslqtytcnvnhkpsntkvdkrvepks
- Chain 'C':
No sequence available.