PDB entry 1u8p

View 1u8p on RCSB PDB site
Description: Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide ECDKWCS
Class: immune system
Keywords: Fab complex, HIV-1 Neutralization, gp41 Peptide, IMMUNE SYSTEM
Deposited on 2004-08-06, released 2004-10-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-01-05, with a file datestamp of 2009-12-31.
Experiment type: XRAY
Resolution: 3.23 Å
R-factor: 0.212
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: antibody 2f5 (light chain)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1U8P (0-213)
    Domains in SCOPe 2.08: d1u8pa1, d1u8pa2
  • Chain 'B':
    Compound: antibody 2f5 (heavy chain)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1U8P (0-234)
    Domains in SCOPe 2.08: d1u8pb1, d1u8pb2
  • Chain 'C':
    Compound: gp41 peptide
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • PDB 1U8P (0-6)

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1u8pA (A:)
alqltqspsslsasvgdrititcrasqgvtsalawyrqkpgsppqlliydasslesgvps
rfsgsgsgteftltistlrpedfatyycqqlhfyphtfgggtrvdvrrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyecevthqglsspvtksfnrgec

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1u8pB (B:)
ritlkesgpplvkptqtltltcsfsgfslsdfgvgvgwirqppgkalewlaiiysdddkr
yspslntrltitkdtsknqvvlvmtrvspvdtatyfcahrrgpttlfgvpiargpvnamd
vwgqgitvtisststkgpsvfplapsskstagaaaalgclvkdyfpepvtvswnsgalts
gvhtfpavlqssglyslssvvtvpssslgtqtytcnvnhkpsntkvdkrvepksc

    Sequence, based on observed residues (ATOM records): (download) 
    >1u8pB (B:)
ritlkesgpplvkptqtltltcsfsgfslsdfgvgvgwirqppgkalewlaiiysdddkr
yspslntrltitkdtsknqvvlvmtrvspvdtatyfcahrrgpttlfgvpiargpvnamd
vwgqgitvtisststkgpsvfplapgaaaalgclvkdyfpepvtvswnsgaltsgvhtfp
avlqssglyslssvvtvpssslqtytcnvnhkpsntkvdkrvepksc

  • Chain 'C':
    No sequence available.