PDB entry 1u8g

View 1u8g on RCSB PDB site
Description: Crystal structure of a HIV-1 Protease in complex with peptidomimetic inhibitor KI2-PHE-GLU-GLU-NH2
Class: hydrolase
Keywords: hydrolase/hydrolase inhibitor; aspartyl protease; human immunodeficiency virus; inhibitor design
Deposited on 2004-08-06, released 2004-11-02
The last revision prior to the SCOP 1.73 freeze date was dated 2004-11-09, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.211
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: protease retropepsin
  Species: HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
  Gene: gag-pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
  Domains in SCOP 1.73: d1u8ga_
• Chain 'B':
  Compound: protease retropepsin
  Species: HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
  Gene: gag-pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
  Domains in SCOP 1.73: d1u8gb_
• Chain 'I':
  Compound: peptidomimetic inhibitor KI2-PHE-GLU-GLU-NH2
  
• Heterogens: NH2, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1u8gA (A:)
  pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
  qilieicghkaigtvlvgptpvniigrnlltqigctlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1u8gB (B:)
  pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
  qilieicghkaigtvlvgptpvniigrnlltqigctlnf
  

  
  
• Chain 'I':
  No sequence available.