PDB entry 1u67

View 1u67 on RCSB PDB site
Description: Crystal Structure of Arachidonic Acid Bound to a Mutant of Prostagladin H Synthase-1 that Forms Predominantly 11-HPETE.
Class: oxidoreductase
Keywords: cyclooxgenase, arachidonic acid, heme, eicosanoid, 11-HETE, COX-1, COX-2, OXIDOREDUCTASE
Deposited on 2004-07-29, released 2004-09-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Prostaglandin G/H synthase 1 precursor
    Species: Ovis aries [TaxId:9940]
    Gene: PTGS1, COX1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05979
      • see remark 999 (91)
      • engineered (348)
      • engineered (386)
    Domains in SCOPe 2.08: d1u67a1, d1u67a2
  • Heterogens: BOG, COH, ACD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1u67A (A:)
msrqsislrfpllllllspspvfsadpgapapvnpccyypcqhqgicvrfgldryqcdct
rtgysgpnctipeiwtwlrttlrpspsfihfllthgrwlwdfvnatfirdtlmrlvltvr
snlipspptyniahdyiswesfsnvsyytrilpsvprdcptpmgtkgkkqlpdaeflsrr
fllrrkfipdpqgtnlmfaffaqhfthqffktsgkmgpgftkalghgvdlghiygdnler
qyqlrlfkdgklkyqmlngevyppsveeapvlmhyprgippqsqmavgqevfgllpglml
yatiwlrehnrvcdllkaehptwgdeqlfqtarliligetikivieeyaqqlsgyflqlk
fdpellfgaqfqyrnriamefnqlyhfhplmpdsfrvgpqdysyeqflfntsmlvdygve
alvdafsrqpagrigggrnidhhilhvavdvikesrvlrlqpfneyrkrfgmkpytsfqe
ltgekemaaeleelygdidalefypglllekchpnsifgesmiemgapfslkgllgnpic
speywkastfggevgfnlvktatlkklvclntktcpyvsfhvpdprqedrpgverpptel

    Sequence, based on observed residues (ATOM records): (download) 
    >1u67A (A:)
pvnpccyypcqhqgicvrfgldryqcdctrtgysgpnctipeiwtwlrttlrpspsfihf
llthgrwlwdfvnatfirdtlmrlvltvrsnlipspptyniahdyiswesfsnvsyytri
lpsvprdcptpmgtkgkkqlpdaeflsrrfllrrkfipdpqgtnlmfaffaqhfthqffk
tsgkmgpgftkalghgvdlghiygdnlerqyqlrlfkdgklkyqmlngevyppsveeapv
lmhyprgippqsqmavgqevfgllpglmlyatiwlrehnrvcdllkaehptwgdeqlfqt
arliligetikivieeyaqqlsgyflqlkfdpellfgaqfqyrnriamefnqlyhfhplm
pdsfrvgpqdysyeqflfntsmlvdygvealvdafsrqpagrigggrnidhhilhvavdv
ikesrvlrlqpfneyrkrfgmkpytsfqeltgekemaaeleelygdidalefypglllek
chpnsifgesmiemgapfslkgllgnpicspeywkastfggevgfnlvktatlkklvcln
tktcpyvsfhvpd