PDB entry 1u5i

View 1u5i on RCSB PDB site
Description: Crystal Structure analysis of rat m-calpain mutant Lys10 Thr
Class: Hydrolase
Keywords: calpain, sulfhydryl protease, crystal structure, Hydrolase
Deposited on 2004-07-27, released 2005-01-18
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.86 Å
R-factor: 0.196
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Calpain 2, large [catalytic] subunit precursor
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07009 (Start-699)
      • engineered (9)
      • engineered (104)
    Domains in SCOPe 2.04: d1u5ia1, d1u5ia2, d1u5ia3
  • Chain 'B':
    Compound: Calpain small subunit 1
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1u5ib_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1u5iA (A:)
magiamklatdreaaeglgsheraikylnqdyetlrnecleagalfqdpsfpalpsslgf
kelgpyssktrgiewkrpteicadpqfiiggatrtdicqgalgdswllaaiasltlneei
larvvpldqsfqenyagifhfqfwqygewvevvvddrlptkdgellfvhsaegsefwsal
lekayakingcyealsggattegfedftggiaewyelrkpppnlfkiiqkalekgsllgc
siditsaadseavtyqklvkghaysvtgaeevessgslqklirirnpwgqvewtgkwndn
cpswntvdpevranlterqedgefwmsfsdflrhysrleicnltpdtltcdsykkwkltk
mdgnwrrgstaggcrnypntfwmnpqylikleeededdedgergctflvgliqkhrrrqr
kmgedmhtigfgiyevpeeltgqtnihlsknfflttrarersdtfinlrevlnrfklppg
eyvlvpstfephkngdfcirvfsekkadyqtvddeieanieeieaneedigdgfrrlfaq
lagedaeisafelqtilrrvlakrediksdgfsietckimvdmldedgsgklglkefyil
wtkiqkyqkiyreidvdrsgtmnsyemrkaleeagfklpcqlhqvivarfaddeliidfd
nfvrclvrleilfkifkqldpentgtiqldliswlsfsvl

    Sequence, based on observed residues (ATOM records): (download) 
    >1u5iA (A:)
agiamklatdreaaeglgsheraikylnqdyetlrnecleagalfqdpsfpalpsslgfk
elgpyssktrgiewkrpteicadpqfiiggatrtdicqgalgdswllaaiasltlneeil
arvvpldqsfqenyagifhfqfwqygewvevvvddrlptkdgellfvhsaegsefwsall
ekayakingcyealsggattegfedftggiaewyelrkpppnlfkiiqkalekgsllgcs
idighaysvtgaeevqklirirnpwgqgefwmsfsdflrhysrleicnltpdtltcdsyk
kwkltkmdgnwrrgstaggcrnypntfwmnpqylikleeededdedgergctflvgliqk
hrrrqrkmgedmhtigfgiyevsknffltersdtfinlrevlnrfklppgeyvlvpstfe
phkngdfcirvfsekkadyqtvddeieanieeianeedigdgfrrlfaqlagedaeisaf
elqtilrrvlakksdgfsietckimvdmldedgsgklglkefyilwtkiqkyqkiyreid
vdrsgtmnsyemrkaleeagfklpcqlhqvivarfaddeliidfdnfvrclvrleilfki
fkqldpentgtiqldliswlsfsvl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1u5iB (B:)
mhysnieaneseeerqfrklfvqlagddmevsatelmnilnkvvtrhpdlktdgfgidtc
rsmvavmdsdttgklgfeefkylwnnikkwqgiykrfdtdrsgtigsnelpgafeaagfh
lnqhiysmiirrysdetgnmdfdnfisclvrldamfrafrsldkngtgqiqvniqewlql
tmys

    Sequence, based on observed residues (ATOM records): (download) 
    >1u5iB (B:)
neseeerqfrklfvqlagddmevsatelmnilnkvvtrhpdlktdgfgidtcrsmvavmd
sdttgklgfeefkylwnnikkwqgiykrfdtdrsgtigsnelpgafeaagfhlnqhiysm
iirrysdetgnmdfdnfisclvrldamfrafrsldkngtgqiqvniqewlqltmys