PDB entry 1u45

View 1u45 on RCSB PDB site
Description: 8oxoguanine at the pre-insertion site of the polymerase active site
Class: transferase/DNA
Keywords: DNA polymerase I; DNA replication; klenow fragment; protein-DNA complex; 8oxoguanine; DNA lesion; translation replication, TRANSFERASE-DNA COMPLEX
Deposited on 2004-07-23, released 2004-09-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.01 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase I
    Species: Geobacillus stearothermophilus [TaxId:1422]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1u45a1, d1u45a2
  • Chain 'B':
    Compound: DNA primer strand
  • Chain 'C':
    Compound: DNA template strand with 8-oxoguanine
  • Heterogens: SO4, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1u45A (A:)
aamaftladrvteemladkaalvvevveenyhdapivgiavvnehgrfflrpetaladpq
fvawlgdetkkksmfdskraavalkwkgielcgvsfdlllaaylldpaqgvddvaaaakm
kqyeavrpdeavygkgakravpdepvlaehlvrkaaaiwelerpfldelrrneqdrllve
leqplssilaemefagvkvdtkrleqmgkelaeqlgtveqriyelagqefninspkqlgv
ilfeklqlpvlkktktgystsadvleklapyheivenilhyrqlgklqstyiegllkvvr
pdtkkvhtifnqaltqtgrlsstepnlqnipirleegrkirqafvpsesdwlifaadysq
ielrvlahiaeddnlmeafrrdldihtktamdifqvsedevtpnmrrqakavnfgivygi
sdyglaqnlnisrkeaaefieryfesfpgvkrymenivqeakqkgyvttllhrrrylpdi
tsrnfnvrsfaermamntpiqgsaadiikkamidlnarlkeerlqahlllqvhdelilea
pkeemerlcrlvpevmeqavtlrvplkvdyhygstwydak

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.