PDB entry 1u41

View 1u41 on RCSB PDB site
Description: Crystal stucture of YLGV mutant of dimerisation domain of NF-kB p50 transcription factor
Class: transcription
Keywords: transcription factor; nf-kb; dimerization domain; intertwined folding
Deposited on 2004-07-23, released 2004-08-17
The last revision prior to the SCOP 1.75 freeze date was dated 2004-08-17, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.176
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nuclear factor NF-kappa-B p105 subunit
    Species: MUS MUSCULUS
    Gene: Nfkb1, 18033
    Database cross-references and differences (RAF-indexed):
    • Uniprot P25799 (Start-105)
      • engineered (63)
    Domains in SCOP 1.75: d1u41a_
  • Chain 'B':
    Compound: Nuclear factor NF-kappa-B p105 subunit
    Species: MUS MUSCULUS
    Gene: Nfkb1, 18033
    Database cross-references and differences (RAF-indexed):
    • Uniprot P25799 (Start-105)
      • engineered (63)
    Domains in SCOP 1.75: d1u41b_
  • Chain 'C':
    Compound: Nuclear factor NF-kappa-B p105 subunit
    Species: MUS MUSCULUS
    Gene: Nfkb1, 18033
    Database cross-references and differences (RAF-indexed):
    • Uniprot P25799 (Start-105)
      • engineered (63)
    Domains in SCOP 1.75: d1u41c_
  • Chain 'D':
    Compound: Nuclear factor NF-kappa-B p105 subunit
    Species: MUS MUSCULUS
    Gene: Nfkb1, 18033
    Database cross-references and differences (RAF-indexed):
    • Uniprot P25799 (0-105)
      • engineered (63)
    Domains in SCOP 1.75: d1u41d_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1u41A (A:)
asnlkivrmdrtagcvtggeeiyllcdkvqkddiqirfyeeeenggvwegfgdfsptdvh
rqfgivfktpkykdvnitkpasvfvqlrrksdletsepkpflyype

    Sequence, based on observed residues (ATOM records): (download) 
    >1u41A (A:)
nlkivrmdrtagcvtggeeiyllcdkvqkddiirfyeeeenggvwegfgdfsptdvhrqf
givfktpkykdvnitkpasvfvqlrrksdletsepkpflyype

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1u41B (B:)
asnlkivrmdrtagcvtggeeiyllcdkvqkddiqirfyeeeenggvwegfgdfsptdvh
rqfgivfktpkykdvnitkpasvfvqlrrksdletsepkpflyype

    Sequence, based on observed residues (ATOM records): (download) 
    >1u41B (B:)
nlkivrmdrtagcvtggeeiyllcdkvqkddiqirfyeeegvwegfgdfsptdvhrqfgi
vfktpkykdvnitkpasvfvqlrrksdletsepkpflyype

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1u41C (C:)
asnlkivrmdrtagcvtggeeiyllcdkvqkddiqirfyeeeenggvwegfgdfsptdvh
rqfgivfktpkykdvnitkpasvfvqlrrksdletsepkpflyype

    Sequence, based on observed residues (ATOM records): (download) 
    >1u41C (C:)
lkivrmdrtagcvtggeeiyllcdkvqkddiqirfyevwegfgdfsptdvhrqfgivfkt
pkykdvnitkpasvfvqlrrksdletsepkpflyype

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1u41D (D:)
asnlkivrmdrtagcvtggeeiyllcdkvqkddiqirfyeeeenggvwegfgdfsptdvh
rqfgivfktpkykdvnitkpasvfvqlrrksdletsepkpflyype

    Sequence, based on observed residues (ATOM records): (download) 
    >1u41D (D:)
asnlkivrmdrtagcvtggeeiyllcdkvqkddiqirfyeeegvwegfgdfsptdvhrqf
givfktpkykdvnitkpasvfvqlrrksdletsepkpflyype