PDB entry 1u2z

View 1u2z on RCSB PDB site
Description: Crystal structure of histone K79 methyltransferase Dot1p from yeast
Class: transferase
Keywords: Histone methyltransferase, Nucleosome
Deposited on 2004-07-20, released 2004-09-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.213
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone-lysine N-methyltransferase, H3 lysine-79 specific
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: dot1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1u2za_
  • Chain 'B':
    Compound: Histone-lysine N-methyltransferase, H3 lysine-79 specific
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: dot1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1u2zb_
  • Chain 'C':
    Compound: Histone-lysine N-methyltransferase, H3 lysine-79 specific
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: dot1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1u2zc_
  • Heterogens: SAH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1u2zA (A:)
mghhhhhhkkplkkgrankkndrdspsstfvdwngpclrlqyplfdieylrsheiysgtp
iqsislrtnspqptsltsdndtssvttaklqsilfsnymeeykvdfkrstaiynpmseig
klieysclvflpspyaeqlketilpdlnasfdnsdtkgfvnainlynkmireiprqriid
hletidkiprsfihdflhivytrsihpqanklkhykafsnyvygellpnflsdvyqqcql
kkgdtfmdlgsgvgncvvqaalecgcalsfgceimddasdltilqyeelkkrcklygmrl
nnvefslkksfvdnnrvaelipqcdvilvnnflfdedlnkkvekilqtakvgckiislks
lrsltyqinfynvenifnrlkvqrydlkedsvswthsggeyyistvmedvdeslfspaar
grrnrgtpvkytr

    Sequence, based on observed residues (ATOM records): (download) 
    >1u2zA (A:)
sstfvdwngpclrlqyplfdieylrsheiysgtpiqsislrttaklqsilfsnymeeykv
dfkrstaiynpmseigklieysclvflpspyaeqlketilpdlnasfdnsdtkgfvnain
lynkmireiprqriidhletidkiprsfihdflhivytrsihpqanklkhykafsnyvyg
ellpnflsdvyqqcqlkkgdtfmdlgsgvgncvvqaalecgcalsfgceimddasdltil
qyeelkkrcklygmrlnnvefslkksfvdnnrvaelipqcdvilvnnflfdedlnkkvek
ilqtakvgckiislkslrsltyqinfynvenifnrlkvqrydlkedsvswthsggeyyis
tvmedvdeslfsparvkyt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1u2zB (B:)
mghhhhhhkkplkkgrankkndrdspsstfvdwngpclrlqyplfdieylrsheiysgtp
iqsislrtnspqptsltsdndtssvttaklqsilfsnymeeykvdfkrstaiynpmseig
klieysclvflpspyaeqlketilpdlnasfdnsdtkgfvnainlynkmireiprqriid
hletidkiprsfihdflhivytrsihpqanklkhykafsnyvygellpnflsdvyqqcql
kkgdtfmdlgsgvgncvvqaalecgcalsfgceimddasdltilqyeelkkrcklygmrl
nnvefslkksfvdnnrvaelipqcdvilvnnflfdedlnkkvekilqtakvgckiislks
lrsltyqinfynvenifnrlkvqrydlkedsvswthsggeyyistvmedvdeslfspaar
grrnrgtpvkytr

    Sequence, based on observed residues (ATOM records): (download) 
    >1u2zB (B:)
stfvdwngpclrlqyplfdieylrsheiysgtpiqsislrtttaklqsilfsnymeeykv
dfkrstaiynpmseigklieysclvflpspyaeqlketilpdlnasfdnsdtkgfvnain
lynkmireiprqriidhletidkiprsfihdflhivytrsihpqanklkhykafsnyvyg
ellpnflsdvyqqcqlkkgdtfmdlgsgvgncvvqaalecgcalsfgceimddasdltil
qyeelkkrcklygmrlnnvefslkksfvdnnrvaelipqcdvilvnnflfdedlnkkvek
ilqtakvgckiislkslrsltyqinfynvenifnrlkvqrydlkedsvswthsggeyyis
tvmedvdeslfsprpvkyt

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1u2zC (C:)
mghhhhhhkkplkkgrankkndrdspsstfvdwngpclrlqyplfdieylrsheiysgtp
iqsislrtnspqptsltsdndtssvttaklqsilfsnymeeykvdfkrstaiynpmseig
klieysclvflpspyaeqlketilpdlnasfdnsdtkgfvnainlynkmireiprqriid
hletidkiprsfihdflhivytrsihpqanklkhykafsnyvygellpnflsdvyqqcql
kkgdtfmdlgsgvgncvvqaalecgcalsfgceimddasdltilqyeelkkrcklygmrl
nnvefslkksfvdnnrvaelipqcdvilvnnflfdedlnkkvekilqtakvgckiislks
lrsltyqinfynvenifnrlkvqrydlkedsvswthsggeyyistvmedvdeslfspaar
grrnrgtpvkytr

    Sequence, based on observed residues (ATOM records): (download) 
    >1u2zC (C:)
sstfvdwngpclrlqyplfdieylrsheiysgtpiqsislrtttaklqsilfsnymeeyk
vdfkrstaiynpmseigklieysclvflpspyaeqlketilpdlnasfdnsdtkgfvnai
nlynkmireiprqriidhletidkiprsfihdflhivytrsihpqanklkhykafsnyvy
gellpnflsdvyqqcqlkkgdtfmdlgsgvgncvvqaalecgcalsfgceimddasdlti
lqyeelkkrcklygmrlnnvefslkksfvdnnrvaelipqcdvilvnnflfdedlnkkve
kilqtakvgckiislkslrsltyqinfynvenifnrlkvqrydlkedsvswthsggeyyi
stvmedvdeslfspaarrtpvkytr