PDB entry 1tzs
View 1tzs on RCSB PDB site
Description: Crystal Structure of an activation intermediate of Cathepsin E
Class: Hydrolase
Keywords: Hydrolase, aspartic protease, activation intermediate
Deposited on
2004-07-12, released
2005-07-12
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.198
AEROSPACI score: 0.36
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Cathepsin E
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1tzsa_ - Chain 'P':
Compound: activation peptide from Cathepsin E
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Chain 'X':
Compound: 23-mer peptide from PelB-IgG kappa light chain fusion protein
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1tzsA (A:)
iqftescsmdqsakeplinyldmeyfgtisigsppqnftvifdtgssnlwvpsvyctspa
ckthsrfqpsqsstysqpgqsfsiqygtgslsgiigadqvsvegltvvgqqfgesvtepg
qtfvdaefdgilglgypslavggvtpvfdnmmaqnlvdlpmfsvymssnpeggagselif
ggydhshfsgslnwvpvtkqaywqialdniqvggtvmfcsegcqaivdtgtslitgpsdk
ikqlqnaigaapvdgeyavecanlnvmpdvtftingvpytlsptaytlldfvdgmqfcss
gfqgldihppagplwilgdvfirqfysvfdrgnnrvglapavpwshpqfek
Sequence, based on observed residues (ATOM records): (download)
>1tzsA (A:)
keplinyldmeyfgtisigsppqnftvifdtgssnlwvpsvyctspackthsrfqpsqss
tysqpgqsfsiqygtgslsgiigadqvsvegltvvgqqfgesvtepgqtfvdaefdgilg
lgypslavggvtpvfdnmmaqnlvdlpmfsvymssnpgagselifggydhshfsgslnwv
pvtkqaywqialdniqvggtvmfcsegcqaivdtgtslitgpsdkikqlqnaigaapvdg
eyavecanlnvmpdvtftingvpytlsptaytlldqfcssgfqgldihppagplwilgdv
firqfysvfdrgnnrvglapav
- Chain 'P':
No sequence available.
- Chain 'X':
No sequence available.