PDB entry 1tzi

View 1tzi on RCSB PDB site
Description: Crystal Structure of the Fab YADS2 Complexed with h-VEGF
Class: immune system
Keywords: phage display, antibody library, protein engineering, immune system
Deposited on 2004-07-10, released 2004-08-31
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.22
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fab YADS2 Light Chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1TZI (0-213)
    Domains in SCOPe 2.03: d1tzia1, d1tzia2
  • Chain 'B':
    Compound: Fab YADS2 Heavy Chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1TZI (0-221)
    Domains in SCOPe 2.03: d1tzib1, d1tzib2
  • Chain 'V':
    Compound: Vascular Endothelial Growth Factor A
    Species: Homo sapiens [TaxId:9606]
    Gene: VEGF, VEGFA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1tziv_

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1tziA (A:)
    diqmtqspsslsasvgdrvtitcrasqsyayavawyqqkpgkapklliydasylysgvps
    rfsgsgsgtdftltisslqpedfatyycqqaysspdtfgqgtkveikrtvaapsvfifpp
    sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
    lskadyekhkvyacevthqglsspvtksfnrgec
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1tziB (B:)
    evqlvesggglvqpggslrlscaasgfaiydydihwvrqapgkglewvadiapyagatay
    adsvkgrftisadtskntaylqmnslraedtavyycsrssyayyaamdywgqgtlvtvss
    astkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
    glyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepks
    

  • Chain 'V':
    Sequence, based on SEQRES records: (download)
    >1tziV (V:)
    gqnhhevvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggccndegle
    cvpteesnitmqimrikphqgqhigemsflqhnkcecrpkkd
    

    Sequence, based on observed residues (ATOM records): (download)
    >1tziV (V:)
    evvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggccndeglecvpte
    esnitmqimrikphqgqhigemsflqhnkcecrpkkd