PDB entry 1txt

View 1txt on RCSB PDB site
Description: Staphylococcus aureus 3-hydroxy-3-methylglutaryl-CoA synthase
Class: lyase
Keywords: HMG-CoA synthase; HMGS, coenzyme A; thiolase fold; condensing enzyme; cholesterol biosynthesis
Deposited on 2004-07-06, released 2004-08-31
The last revision prior to the SCOP 1.73 freeze date was dated 2005-02-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.191
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-hydroxy-3-methylglutaryl-CoA synthase
    Species: Staphylococcus aureus
    Gene: mvaS
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9FD87 (Start-387)
      • modified residue (110)
      • conflict (319)
    Domains in SCOP 1.73: d1txta1, d1txta2
  • Chain 'B':
    Compound: 3-hydroxy-3-methylglutaryl-CoA synthase
    Species: Staphylococcus aureus
    Gene: mvaS
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9FD87 (Start-387)
      • modified residue (110)
      • conflict (319)
    Domains in SCOP 1.73: d1txtb1, d1txtb2
  • Chain 'C':
    Compound: 3-hydroxy-3-methylglutaryl-CoA synthase
    Species: Staphylococcus aureus
    Gene: mvaS
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9FD87 (Start-387)
      • modified residue (110)
      • conflict (319)
    Domains in SCOP 1.73: d1txtc1, d1txtc2
  • Chain 'D':
    Compound: 3-hydroxy-3-methylglutaryl-CoA synthase
    Species: Staphylococcus aureus
    Gene: mvaS
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9FD87 (Start-387)
      • modified residue (110)
      • conflict (319)
    Domains in SCOP 1.73: d1txtd1, d1txtd2
  • Heterogens: CAA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1txtA (A:)
mtigidkinfyvpkyyvdmaklaearqvdpnkfligigqtemavspvnqdivsmganaak
diitdedkkkigmvivatesavdaakaaavqihnllgiqpfarcfemkeacyaatpaiql
akdylatrpnekvlviatdtaryglnsggeptqgagavamviahnpsilalnedavayte
dvydfwrptghkyplvdgalskdayirsfqqswneyakrqgksladfaslcfhvpftkmg
kkalesiidnadettqerlrsgyedavdynryvgniytgslylslisllenrdlqageti
glfsygsgsvvefysatlvegykdhldqaahkallnnrtevsvdayetffkrfddvefde
eqdavhedrhifylsniennvreyhrpe

    Sequence, based on observed residues (ATOM records): (download) 
    >1txtA (A:)
tigidkinfyvpkyyvdmaklaearqvdpnkfligigqtemavspvnqdivsmganaakd
iitdedkkkigmvivatesavdaakaaavqihnllgiqpfarcfemkeacyaatpaiqla
kdylatrpnekvlviatdtaryglnsggeptqgagavamviahnpsilalnedavayted
vydfwrptghkyplvdgalskdayirsfqqswneyakrqgksladfaslcfhvpftkmgk
kalesiidnadettqerlrsgyedavdynryvgniytgslylslisllenrdlqagetig
lfsygsgsvvefysatlvegykdhldqaahkallnnrtevsvdayetffkrfddvefdee
qdavhedrhifylsniennvreyhrpe

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1txtB (B:)
mtigidkinfyvpkyyvdmaklaearqvdpnkfligigqtemavspvnqdivsmganaak
diitdedkkkigmvivatesavdaakaaavqihnllgiqpfarcfemkeacyaatpaiql
akdylatrpnekvlviatdtaryglnsggeptqgagavamviahnpsilalnedavayte
dvydfwrptghkyplvdgalskdayirsfqqswneyakrqgksladfaslcfhvpftkmg
kkalesiidnadettqerlrsgyedavdynryvgniytgslylslisllenrdlqageti
glfsygsgsvvefysatlvegykdhldqaahkallnnrtevsvdayetffkrfddvefde
eqdavhedrhifylsniennvreyhrpe

    Sequence, based on observed residues (ATOM records): (download) 
    >1txtB (B:)
tigidkinfyvpkyyvdmaklaearqvdpnkfligigqtemavspvnqdivsmganaakd
iitdedkkkigmvivatesavdaakaaavqihnllgiqpfarcfemkeacyaatpaiqla
kdylatrpnekvlviatdtaryglnsggeptqgagavamviahnpsilalnedavayted
vydfwrptghkyplvdgalskdayirsfqqswneyakrqgksladfaslcfhvpftkmgk
kalesiidnadettqerlrsgyedavdynryvgniytgslylslisllenrdlqagetig
lfsygsgsvvefysatlvegykdhldqaahkallnnrtevsvdayetffkrfddvefdee
qdavhedrhifylsniennvreyhrpe

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1txtC (C:)
mtigidkinfyvpkyyvdmaklaearqvdpnkfligigqtemavspvnqdivsmganaak
diitdedkkkigmvivatesavdaakaaavqihnllgiqpfarcfemkeacyaatpaiql
akdylatrpnekvlviatdtaryglnsggeptqgagavamviahnpsilalnedavayte
dvydfwrptghkyplvdgalskdayirsfqqswneyakrqgksladfaslcfhvpftkmg
kkalesiidnadettqerlrsgyedavdynryvgniytgslylslisllenrdlqageti
glfsygsgsvvefysatlvegykdhldqaahkallnnrtevsvdayetffkrfddvefde
eqdavhedrhifylsniennvreyhrpe

    Sequence, based on observed residues (ATOM records): (download) 
    >1txtC (C:)
tigidkinfyvpkyyvdmaklaearqvdpnkfligigqtemavspvnqdivsmganaakd
iitdedkkkigmvivatesavdaakaaavqihnllgiqpfarcfemkeacyaatpaiqla
kdylatrpnekvlviatdtaryglnsggeptqgagavamviahnpsilalnedavayted
vydfwrptghkyplvdgalskdayirsfqqswneyakrqgksladfaslcfhvpftkmgk
kalesiidnadettqerlrsgyedavdynryvgniytgslylslisllenrdlqagetig
lfsygsgsvvefysatlvegykdhldqaahkallnnrtevsvdayetffkrfddvefdee
qdavhedrhifylsniennvreyhrpe

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1txtD (D:)
mtigidkinfyvpkyyvdmaklaearqvdpnkfligigqtemavspvnqdivsmganaak
diitdedkkkigmvivatesavdaakaaavqihnllgiqpfarcfemkeacyaatpaiql
akdylatrpnekvlviatdtaryglnsggeptqgagavamviahnpsilalnedavayte
dvydfwrptghkyplvdgalskdayirsfqqswneyakrqgksladfaslcfhvpftkmg
kkalesiidnadettqerlrsgyedavdynryvgniytgslylslisllenrdlqageti
glfsygsgsvvefysatlvegykdhldqaahkallnnrtevsvdayetffkrfddvefde
eqdavhedrhifylsniennvreyhrpe

    Sequence, based on observed residues (ATOM records): (download) 
    >1txtD (D:)
tigidkinfyvpkyyvdmaklaearqvdpnkfligigqtemavspvnqdivsmganaakd
iitdedkkkigmvivatesavdaakaaavqihnllgiqpfarcfemkeacyaatpaiqla
kdylatrpnekvlviatdtaryglnsggeptqgagavamviahnpsilalnedavayted
vydfwrptghkyplvdgalskdayirsfqqswneyakrqgksladfaslcfhvpftkmgk
kalesiidnadettqerlrsgyedavdynryvgniytgslylslisllenrdlqagetig
lfsygsgsvvefysatlvegykdhldqaahkallnnrtevsvdayetffkrfddvefdee
qdavhedrhifylsniennvreyhrpe