PDB entry 1tx6

View 1tx6 on RCSB PDB site
Description: trypsin:BBI complex
Class: hydrolase/protein binding
Keywords: anticarcinogenic activity, double-headed inhibitor, gene duplication, monocotyledonous plant, inhibitory loop
Deposited on 2004-07-02, released 2005-03-08
The last revision prior to the SCOP 1.73 freeze date was dated 2005-03-08, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.223
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Trypsin
    Species: SUS SCROFA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1tx6a1
  • Chain 'B':
    Compound: Trypsin
    Species: SUS SCROFA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1tx6b1
  • Chain 'C':
    Compound: Trypsin
    Species: SUS SCROFA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1tx6c1
  • Chain 'D':
    Compound: Trypsin
    Species: SUS SCROFA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1tx6d1
  • Chain 'I':
    Compound: Bowman-Birk type trypsin inhibitor
    Species: Hordeum vulgare
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12940 (Start-124)
      • see remark 999 (41)
    Domains in SCOP 1.73: d1tx6i1
  • Chain 'J':
    Compound: Bowman-Birk type trypsin inhibitor
    Species: Hordeum vulgare
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12940 (Start-124)
      • see remark 999 (41)
    Domains in SCOP 1.73: d1tx6j1
  • Heterogens: CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1tx6A (A:)
    ivggytcaansipyqvslnsgshfcggslinsqwvvsaahcyksriqvrlgehnidvleg
    neqfinaakiithpnfngntldndimliklsspatlnsrvatvslprscaaagteclisg
    wgntkssgssypsllqclkapvlsdssckssypgqitgnmicvgfleggkdscqgdsggp
    vvcngqlqgivswgygcaqknkpgvytkvcnyvnwiqqtiaan
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1tx6B (B:)
    ivggytcaansipyqvslnsgshfcggslinsqwvvsaahcyksriqvrlgehnidvleg
    neqfinaakiithpnfngntldndimliklsspatlnsrvatvslprscaaagteclisg
    wgntkssgssypsllqclkapvlsdssckssypgqitgnmicvgfleggkdscqgdsggp
    vvcngqlqgivswgygcaqknkpgvytkvcnyvnwiqqtiaan
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1tx6C (C:)
    ivggytcaansipyqvslnsgshfcggslinsqwvvsaahcyksriqvrlgehnidvleg
    neqfinaakiithpnfngntldndimliklsspatlnsrvatvslprscaaagteclisg
    wgntkssgssypsllqclkapvlsdssckssypgqitgnmicvgfleggkdscqgdsggp
    vvcngqlqgivswgygcaqknkpgvytkvcnyvnwiqqtiaan
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1tx6D (D:)
    ivggytcaansipyqvslnsgshfcggslinsqwvvsaahcyksriqvrlgehnidvleg
    neqfinaakiithpnfngntldndimliklsspatlnsrvatvslprscaaagteclisg
    wgntkssgssypsllqclkapvlsdssckssypgqitgnmicvgfleggkdscqgdsggp
    vvcngqlqgivswgygcaqknkpgvytkvcnyvnwiqqtiaan
    

  • Chain 'I':
    Sequence, based on SEQRES records: (download)
    >1tx6I (I:)
    agkkrpwkccdeavctrsippictcmdevfecpktckscgpsmgdpsrricqdqyvgdpg
    picrpweccdkaictrsnpptcrcvdevkkcaptcktclpsrsrpsrrvcidsyfgpvpp
    rctpr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1tx6I (I:)
    rpwkccdeavctrsippictcmdevfecckscgpsmgdpsrricqdqyvgdpgpicrpwe
    ccdkaictrsnpptcrcvdevkkcaptcktclrvcidsyfgpvpprctpr
    

  • Chain 'J':
    Sequence, based on SEQRES records: (download)
    >1tx6J (J:)
    agkkrpwkccdeavctrsippictcmdevfecpktckscgpsmgdpsrricqdqyvgdpg
    picrpweccdkaictrsnpptcrcvdevkkcaptcktclpsrsrpsrrvcidsyfgpvpp
    rctpr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1tx6J (J:)
    rpwkccdeavctrsippictcmdevfectckscgpsmgdpsrricqdqyvgdpgpicrpw
    eccdkaictrsnpptcrcvdevkkcaptcktclpsrrvcidsyfgpvpprctpr