PDB entry 1tx4

View 1tx4 on RCSB PDB site
Description: rho/rhogap/GDP(dot)alf4 complex
Class: complex(gtpase activatn/proto-oncogene)
Keywords: complex (gtpase activation/proto-oncogene), gtpase, transition state, gap, complex(gtpase activatn/proto-oncogene) complex
Deposited on 1997-07-29, released 1998-09-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: 0.169
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: p50-rhogap
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07960 (Start-197)
      • conflict (76)
    Domains in SCOPe 2.08: d1tx4a_
  • Chain 'B':
    Compound: transforming protein rhoa
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61586 (0-176)
      • substitution (22)
    Domains in SCOPe 2.08: d1tx4b_
  • Heterogens: MG, ALF, GDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1tx4A (A:)
rpplpnqqfgvslqhlqeknpeqepipivlretvaylqahalttegifrrsantqvvrev
qqkynmglpvdfdqynalhlpavilktflrelpeplltfdlyphvvgflnidesqrvpat
lqvlqtlpeenyqvlrfltaflvqisahsdqnkmtntnlavvfgpnllwakdaaitlkai
npintftkflldhqgelf

    Sequence, based on observed residues (ATOM records): (download) 
    >1tx4A (A:)
plpnqqfgvslqhlqeknpeqepipivlretvaylqahalttegifrrsantqvvrevqq
kynmglpvdfdqynalhlpavilktflrelpeplltfdlyphvvgflnidesqrvpatlq
vlqtlpeenyqvlrfltaflvqisahsdqnkmtntnlavvfgpnllwakdaaitlkainp
intftkflldhqgelf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1tx4B (B:)
airkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalwdtag
qedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlr
ndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraal

    Sequence, based on observed residues (ATOM records): (download) 
    >1tx4B (B:)
airkklvivgdgacgktcllivnskdqfyvptvfenyvadievdgkqvelalwdtagqed
ydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlrnde
htrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraal