PDB entry 1twi

View 1twi on RCSB PDB site
Description: Crystal structure of Diaminopimelate Decarboxylase from m. jannaschii in co-complex with L-lysine
Class: lyase
Keywords: antibiotic resistance, diaminopimelate decarboxylase, lysine biosynthesis, structural genomics, NYSGXRC, T135, PSI, Protein Structure Initiative, New York SGX Research Center for Structural Genomics, LYASE
Deposited on 2004-07-01, released 2004-07-27
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.157
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: diaminopimelate decarboxylase
    Species: Methanocaldococcus jannaschii [TaxId:2190]
    Gene: LYSA, MJ1097
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q58497 (1-433)
      • initiating methionine (0)
    Domains in SCOPe 2.06: d1twia1, d1twia2
  • Chain 'B':
    Compound: diaminopimelate decarboxylase
    Species: Methanocaldococcus jannaschii [TaxId:2190]
    Gene: LYSA, MJ1097
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q58497 (1-433)
      • initiating methionine (0)
    Domains in SCOPe 2.06: d1twib1, d1twib2
  • Chain 'C':
    Compound: diaminopimelate decarboxylase
    Species: Methanocaldococcus jannaschii [TaxId:2190]
    Gene: LYSA, MJ1097
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q58497 (1-433)
      • initiating methionine (0)
    Domains in SCOPe 2.06: d1twic1, d1twic2
  • Chain 'D':
    Compound: diaminopimelate decarboxylase
    Species: Methanocaldococcus jannaschii [TaxId:2190]
    Gene: LYSA, MJ1097
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q58497 (1-433)
      • initiating methionine (0)
    Domains in SCOPe 2.06: d1twid1, d1twid2
  • Heterogens: MG, LYS, PLP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1twiA (A:)
mlgndtveikdgrffidgydaielaekfgtplyvmseeqikinynryieafkrweeetgk
efivayaykananlaitrllaklgcgadvvsggelyiaklsnvpskkivfngncktkeei
imgieanirafnvdsiselilinetakelgetanvafrinpnvnpkthpkistglkknkf
gldvesgiamkaikmalemeyvnvvgvhchigsqltdispfieetrkvmdfvvelkeegi
eiedvnlggglgipyykdkqiptqkdladaiintmlkykdkvempnlilepgrslvatag
yllgkvhhiketpvtkwvmidagmndmmrpamyeayhhiinckvknekevvsiagglces
sdvfgrdreldkvevgdvlaifdvgaygismannynargrprmvltskkgvflirerety
adliakdivpphll

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1twiB (B:)
mlgndtveikdgrffidgydaielaekfgtplyvmseeqikinynryieafkrweeetgk
efivayaykananlaitrllaklgcgadvvsggelyiaklsnvpskkivfngncktkeei
imgieanirafnvdsiselilinetakelgetanvafrinpnvnpkthpkistglkknkf
gldvesgiamkaikmalemeyvnvvgvhchigsqltdispfieetrkvmdfvvelkeegi
eiedvnlggglgipyykdkqiptqkdladaiintmlkykdkvempnlilepgrslvatag
yllgkvhhiketpvtkwvmidagmndmmrpamyeayhhiinckvknekevvsiagglces
sdvfgrdreldkvevgdvlaifdvgaygismannynargrprmvltskkgvflirerety
adliakdivpphll

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1twiC (C:)
mlgndtveikdgrffidgydaielaekfgtplyvmseeqikinynryieafkrweeetgk
efivayaykananlaitrllaklgcgadvvsggelyiaklsnvpskkivfngncktkeei
imgieanirafnvdsiselilinetakelgetanvafrinpnvnpkthpkistglkknkf
gldvesgiamkaikmalemeyvnvvgvhchigsqltdispfieetrkvmdfvvelkeegi
eiedvnlggglgipyykdkqiptqkdladaiintmlkykdkvempnlilepgrslvatag
yllgkvhhiketpvtkwvmidagmndmmrpamyeayhhiinckvknekevvsiagglces
sdvfgrdreldkvevgdvlaifdvgaygismannynargrprmvltskkgvflirerety
adliakdivpphll

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1twiD (D:)
mlgndtveikdgrffidgydaielaekfgtplyvmseeqikinynryieafkrweeetgk
efivayaykananlaitrllaklgcgadvvsggelyiaklsnvpskkivfngncktkeei
imgieanirafnvdsiselilinetakelgetanvafrinpnvnpkthpkistglkknkf
gldvesgiamkaikmalemeyvnvvgvhchigsqltdispfieetrkvmdfvvelkeegi
eiedvnlggglgipyykdkqiptqkdladaiintmlkykdkvempnlilepgrslvatag
yllgkvhhiketpvtkwvmidagmndmmrpamyeayhhiinckvknekevvsiagglces
sdvfgrdreldkvevgdvlaifdvgaygismannynargrprmvltskkgvflirerety
adliakdivpphll