PDB entry 1tv9

View 1tv9 on RCSB PDB site
Description: human DNA polymerase beta complexed with nicked DNA containing a mismatched template adenine and incoming cytidine
Class: transferase/DNA
Keywords: nucleotidyltransferase, DNA repair, DNA mismatch, base excision repair, transferase/DNA complex
Deposited on 2004-06-29, released 2004-11-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.179
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase beta
    Species: Homo sapiens [TaxId:9606]
    Gene: POLB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1tv9a1, d1tv9a2, d1tv9a3
  • Chain 'D':
    Compound: 5'-d(p*gp*tp*cp*gp*g)-3'
  • Chain 'P':
    Compound: 5'-d(*gp*cp*tp*gp*ap*tp*gp*cp*gp*cp*c)-3'
  • Chain 'T':
    Compound: 5'-d(*cp*cp*gp*ap*cp*ap*gp*cp*gp*cp*ap*tp*cp*ap*gp*c)-3'
  • Heterogens: MG, NA, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1tv9A (A:)
    mskrkapqetlnggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeak
    klpgvgtkiaekideflatgklrklekirqddtsssinfltrvsgigpsaarkfvdegik
    tledlrknedklnhhqriglkyfgdfekripreemlqmqdivlnevkkvdseyiatvcgs
    frrgaessgdmdvllthpsftsestkqpkllhqvveqlqkvhfitdtlskgetkfmgvcq
    lpskndekeyphrridirlipkdqyycgvlyftgsdifnknmrahalekgftineytirp
    lgvtgvageplpvdsekdifdyiqwkyrepkdrse
    

    Sequence, based on observed residues (ATOM records): (download)
    >1tv9A (A:)
    kapqetlnggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeakklpg
    vgtkiaekideflatgklrklekirqddtsssinfltrvsgigpsaarkfvdegiktled
    lrknedklnhhqriglkyfgdfekripreemlqmqdivlnevkkvdseyiatvcgsfrrg
    aessgdmdvllthpsftsestkqpkllhqvveqlqkvhfitdtlskgetkfmgvcqlpsk
    ndekeyphrridirlipkdqyycgvlyftgsdifnknmrahalekgftineytirplgvt
    gvageplpvdsekdifdyiqwkyrepkdrse
    

  • Chain 'D':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.