PDB entry 1tue

View 1tue on RCSB PDB site
Description: The X-ray Structure of the Papillomavirus Helicase in Complex with its Molecular Matchmaker E2
Class: replication
Keywords: Human papillomavirus, helicase, replication, E1E2 complex, AAA+ protein
Deposited on 2004-06-24, released 2004-08-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-07-14, with a file datestamp of 2009-07-10.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.221
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: replication protein e1
    Species: Human papillomavirus - 18 [TaxId:333761]
    Gene: E1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06789 (8-End)
      • expression tag (5-7)
    Domains in SCOPe 2.08: d1tuea1, d1tuea2
  • Chain 'B':
    Compound: Regulatory protein E2
    Species: Human papillomavirus - 18 [TaxId:333761]
    Gene: E2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q80B71 (3-End)
      • expression tag (2)
    Domains in SCOPe 2.08: d1tueb1, d1tueb2
  • Chain 'D':
    Compound: replication protein e1
    Species: Human papillomavirus - 18 [TaxId:333761]
    Gene: E1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1tued_
  • Chain 'E':
    Compound: Regulatory protein E2
    Species: Human papillomavirus - 18 [TaxId:333761]
    Gene: E2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1tuee_
  • Chain 'F':
    Compound: replication protein e1
    Species: Human papillomavirus - 18 [TaxId:333761]
    Gene: E1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1tuef_
  • Chain 'G':
    Compound: Regulatory protein E2
    Species: Human papillomavirus - 18 [TaxId:333761]
    Gene: E2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1tueg_
  • Chain 'H':
    Compound: replication protein e1
    Species: Human papillomavirus - 18 [TaxId:333761]
    Gene: E1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1tueh_
  • Chain 'J':
    Compound: Regulatory protein E2
    Species: Human papillomavirus - 18 [TaxId:333761]
    Gene: E2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1tuej_
  • Chain 'K':
    Compound: replication protein e1
    Species: Human papillomavirus - 18 [TaxId:333761]
    Gene: E1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1tuek_
  • Chain 'L':
    Compound: Regulatory protein E2
    Species: Human papillomavirus - 18 [TaxId:333761]
    Gene: E2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1tuel_
  • Chain 'M':
    Compound: replication protein e1
    Species: Human papillomavirus - 18 [TaxId:333761]
    Gene: E1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1tuem_
  • Chain 'Q':
    Compound: Regulatory protein E2
    Species: Human papillomavirus - 18 [TaxId:333761]
    Gene: E2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1tueq_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1tueA (A:)
gsefgsgsnmsqwirfrcskideggdwrpivqflryqqiefitflgalksflkgtpkknc
lvfcgpantgksyfgmsfihfiqgavisfvnstshfwlepltdtkvamlddatttcwtyf
dtymrnaldgnpisidrkhkpliqlkcppillttnihpakdnrwpylesritvfefpnaf
pfdkngnpvyeindknwkcffertwsrldlhe

    Sequence, based on observed residues (ATOM records): (download) 
    >1tueA (A:)
sgsnmsqwirfrcskideggdwrpivqflryqqiefitflgalksflkgtpkknclvfcg
pantgksyfgmsfihfiqgavisfvnstshfwlepltdtkvamlddatttcwtyfdtymr
naldgnpisidpliqlkcppillttnihpakdnrwpylesritvfefpnafpfdkngnpv
yeindknwkcffertwsrldl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1tueB (B:)
gshmqtpketlserlsalqdkiidhyendskdidsqiqywqlirwenaiffaarehgiqt
lnhqvvpayniskskahkaielqmalqglaqsayktedwtlqdtceelwntepthcfkkg
gqtvqvyfdgnkdncmtyvawdsvyymtdagtwdktatcvshrglyyvkegyntfyiefk
secekygntgtwevhfgnnvidcndsmcstsddtvsat

    Sequence, based on observed residues (ATOM records): (download) 
    >1tueB (B:)
hmqtpketlserlsalqdkiidhyendskdidsqiqywqlirwenaiffaarehgiqtln
hqvvpayniskskahkaielqmalqglaqsayktedwtlqdtceelwntepthcfkkggq
tvqvyfdgnkdncmtyvawdsvyymtdagtwdktatcvshrglyyvkegyntfyiefkse
cekygntgtwevhf

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1tueD (D:)
gsefgsgsnmsqwirfrcskideggdwrpivqflryqqiefitflgalksflkgtpkknc
lvfcgpantgksyfgmsfihfiqgavisfvnstshfwlepltdtkvamlddatttcwtyf
dtymrnaldgnpisidrkhkpliqlkcppillttnihpakdnrwpylesritvfefpnaf
pfdkngnpvyeindknwkcffertwsrldlhe

    Sequence, based on observed residues (ATOM records): (download) 
    >1tueD (D:)
nmsqwirfrcskideggdwrpivqflryqqiefitflgalksflkgtpkknclvfcgpan
tgksyfgmsfihfiqgavisfvnstshfwlepltdtkvamlddatttcwtyfdtymrnal
dgnpisidrkhkpliqlkcppillttnihpakdnrwpylesritvfefpnafpfdkngnp
vyeindknwkcffertwsrldl

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1tueE (E:)
gshmqtpketlserlsalqdkiidhyendskdidsqiqywqlirwenaiffaarehgiqt
lnhqvvpayniskskahkaielqmalqglaqsayktedwtlqdtceelwntepthcfkkg
gqtvqvyfdgnkdncmtyvawdsvyymtdagtwdktatcvshrglyyvkegyntfyiefk
secekygntgtwevhfgnnvidcndsmcstsddtvsat

    Sequence, based on observed residues (ATOM records): (download) 
    >1tueE (E:)
tpketlserlsalqdkiidhyendskdidsqiqywqlirwenaiffaarehgiqtlnhqv
vpayniskskahkaielqmalqglaqsayktedwtlqdtceelwntepthcfkkggqtvq
vyfdgnkdncmtyvawdsvyymtdagtwdktatcvshrglyyvkegyntfyiefksecek
ygntgtwevhfgnnvi

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1tueF (F:)
gsefgsgsnmsqwirfrcskideggdwrpivqflryqqiefitflgalksflkgtpkknc
lvfcgpantgksyfgmsfihfiqgavisfvnstshfwlepltdtkvamlddatttcwtyf
dtymrnaldgnpisidrkhkpliqlkcppillttnihpakdnrwpylesritvfefpnaf
pfdkngnpvyeindknwkcffertwsrldlhe

    Sequence, based on observed residues (ATOM records): (download) 
    >1tueF (F:)
nmsqwirfrcskideggdwrpivqflryqqiefitflgalksflkgtpkknclvfcgpan
tgksyfgmsfihfiqgavisfvnstshfwlepltdtkvamlddatttcwtyfdtymrnal
dgnpkcppillttnihpakdnrwpylesritvfefpnafpfdkngnpvyeindknwkcff
ertwsrld

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >1tueG (G:)
gshmqtpketlserlsalqdkiidhyendskdidsqiqywqlirwenaiffaarehgiqt
lnhqvvpayniskskahkaielqmalqglaqsayktedwtlqdtceelwntepthcfkkg
gqtvqvyfdgnkdncmtyvawdsvyymtdagtwdktatcvshrglyyvkegyntfyiefk
secekygntgtwevhfgnnvidcndsmcstsddtvsat

    Sequence, based on observed residues (ATOM records): (download) 
    >1tueG (G:)
pketlserlsalqdkiidhyendskdidsqiqywqlirwenaiffaarehgiqtlnhqvv
payniskskahkaielqmalqglaqsayktedwtlqdtceelwntepthcfkkggqtvqv
yfdgnkdncmtyvawdsvyymtdagtwdktatcvshrglyyvkegyntfyiefkseceky
gntgtwevhfgnnvid

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1tueH (H:)
gsefgsgsnmsqwirfrcskideggdwrpivqflryqqiefitflgalksflkgtpkknc
lvfcgpantgksyfgmsfihfiqgavisfvnstshfwlepltdtkvamlddatttcwtyf
dtymrnaldgnpisidrkhkpliqlkcppillttnihpakdnrwpylesritvfefpnaf
pfdkngnpvyeindknwkcffertwsrldlhe

    Sequence, based on observed residues (ATOM records): (download) 
    >1tueH (H:)
nmsqwirfrcskideggdwrpivqflryqqiefitflgalksflkgtpkknclvfcgpan
tgksyfgmsfihfiqgavisfvnstshfwlepltdtkvamlddatttcwtyfdtymrnal
dgnpisikcppillttnihpakdnrwpylesritvfefpnafpfdkngnpvyeindknwk
cffertwsrld

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >1tueJ (J:)
gshmqtpketlserlsalqdkiidhyendskdidsqiqywqlirwenaiffaarehgiqt
lnhqvvpayniskskahkaielqmalqglaqsayktedwtlqdtceelwntepthcfkkg
gqtvqvyfdgnkdncmtyvawdsvyymtdagtwdktatcvshrglyyvkegyntfyiefk
secekygntgtwevhfgnnvidcndsmcstsddtvsat

    Sequence, based on observed residues (ATOM records): (download) 
    >1tueJ (J:)
pketlserlsalqdkiidhyendskdidsqiqywqlirwenaiffaarehgiqtlnhqvv
payniskskahkaielqmalqglaqsayktedwtlqdtceelwntepthcfkkggqtvqv
yfdgnkdncmtyvawdsvyymtdagtwdktatcvshrglyyvkegyntfyiefkseceky
gntgtwevhfgnnv

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >1tueK (K:)
gsefgsgsnmsqwirfrcskideggdwrpivqflryqqiefitflgalksflkgtpkknc
lvfcgpantgksyfgmsfihfiqgavisfvnstshfwlepltdtkvamlddatttcwtyf
dtymrnaldgnpisidrkhkpliqlkcppillttnihpakdnrwpylesritvfefpnaf
pfdkngnpvyeindknwkcffertwsrldlhe

    Sequence, based on observed residues (ATOM records): (download) 
    >1tueK (K:)
nmsqwirfrcskideggdwrpivqflryqqiefitflgalksflkgtpkknclvfcgpan
tgksyfgmsfihfiqgavisfvnstshfwlepltdtkvamlddatttcwtyfdtymrnal
dgnpiqlkcppillttnihpakdnrwpylesritvfefpnafpfdkngnpvyeindknwk
cffertwsrldl

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >1tueL (L:)
gshmqtpketlserlsalqdkiidhyendskdidsqiqywqlirwenaiffaarehgiqt
lnhqvvpayniskskahkaielqmalqglaqsayktedwtlqdtceelwntepthcfkkg
gqtvqvyfdgnkdncmtyvawdsvyymtdagtwdktatcvshrglyyvkegyntfyiefk
secekygntgtwevhfgnnvidcndsmcstsddtvsat

    Sequence, based on observed residues (ATOM records): (download) 
    >1tueL (L:)
pketlserlsalqdkiidhyendskdidsqiqywqlirwenaiffaarehgiqtlnhqvv
payniskskahkaielqmalqglaqsayktedwtlqdtceelwntepthcfkkggqtvqv
yfdgnkdncmtyvawdsvyymtdagtwdktatcvshrglyyvkegyntfyiefkseceky
gtgtwevhfgnnv

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >1tueM (M:)
gsefgsgsnmsqwirfrcskideggdwrpivqflryqqiefitflgalksflkgtpkknc
lvfcgpantgksyfgmsfihfiqgavisfvnstshfwlepltdtkvamlddatttcwtyf
dtymrnaldgnpisidrkhkpliqlkcppillttnihpakdnrwpylesritvfefpnaf
pfdkngnpvyeindknwkcffertwsrldlhe

    Sequence, based on observed residues (ATOM records): (download) 
    >1tueM (M:)
nmsqwirfrcskideggdwrpivqflryqqiefitflgalksflkgtpkknclvfcgpan
tgksyfgmsfihfiqgavisfvnstshfwlepltdtkvamlddatttcwtyfdtymrnal
dgnpisidliqlkcppillttnihpakdrwpylesritvfefpnafpfdkngnpvyeind
knwkcffertwsrldl

  • Chain 'Q':
    Sequence, based on SEQRES records: (download) 
    >1tueQ (Q:)
gshmqtpketlserlsalqdkiidhyendskdidsqiqywqlirwenaiffaarehgiqt
lnhqvvpayniskskahkaielqmalqglaqsayktedwtlqdtceelwntepthcfkkg
gqtvqvyfdgnkdncmtyvawdsvyymtdagtwdktatcvshrglyyvkegyntfyiefk
secekygntgtwevhfgnnvidcndsmcstsddtvsat

    Sequence, based on observed residues (ATOM records): (download) 
    >1tueQ (Q:)
pketlserlsalqdkiidhyendskdidsqiqywqlirwenaiffaarehgiqtlnhqvv
payniskskahkaielqmalqglaqsayktedwtlqdtceelwntepthcfkkggqtvqv
yfdgnkdncmtyvawdsvyymtdagtwdktatcvshrglyyvkegyntfyiefkseceky
gntgtwevhfgnnv