PDB entry 1tu8

View 1tu8 on RCSB PDB site
Description: STructure of Onchoverca volvulus Pi-class Glutathione S-transferase with its kompetitive inhibitor s-hexyl-GSH
Class: transferase
Keywords: transferase
Deposited on 2004-06-24, released 2005-01-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.182
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutathione S-transferase 2
    Species: Onchocerca volvulus [TaxId:6282]
    Gene: GST2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P46427 (0-207)
      • see remark 999 (176)
    Domains in SCOPe 2.07: d1tu8a1, d1tu8a2
  • Chain 'B':
    Compound: Glutathione S-transferase 2
    Species: Onchocerca volvulus [TaxId:6282]
    Gene: GST2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P46427 (0-207)
      • see remark 999 (176)
    Domains in SCOPe 2.07: d1tu8b1, d1tu8b2
  • Chain 'C':
    Compound: Glutathione S-transferase 2
    Species: Onchocerca volvulus [TaxId:6282]
    Gene: GST2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P46427 (0-207)
      • see remark 999 (176)
    Domains in SCOPe 2.07: d1tu8c1, d1tu8c2
  • Chain 'D':
    Compound: Glutathione S-transferase 2
    Species: Onchocerca volvulus [TaxId:6282]
    Gene: GST2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P46427 (0-207)
      • see remark 999 (176)
    Domains in SCOPe 2.07: d1tu8d1, d1tu8d2
  • Heterogens: GTX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tu8A (A:)
msykltyfsirglaepirlflvdqdikfiddriakddfssiksqfqfgqlpclydgdqqi
vqsgailrhlarkynlngenemettyidmfcegvrdlhvkytrmiymayetekdpyiksi
lpgelakfekllatrgngrnlilgdkisyadyalfeeldvhqildphcldkfpllkvfhq
rmkdrpklkeycekrdaakvpvngngkq

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tu8B (B:)
msykltyfsirglaepirlflvdqdikfiddriakddfssiksqfqfgqlpclydgdqqi
vqsgailrhlarkynlngenemettyidmfcegvrdlhvkytrmiymayetekdpyiksi
lpgelakfekllatrgngrnlilgdkisyadyalfeeldvhqildphcldkfpllkvfhq
rmkdrpklkeycekrdaakvpvngngkq

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tu8C (C:)
msykltyfsirglaepirlflvdqdikfiddriakddfssiksqfqfgqlpclydgdqqi
vqsgailrhlarkynlngenemettyidmfcegvrdlhvkytrmiymayetekdpyiksi
lpgelakfekllatrgngrnlilgdkisyadyalfeeldvhqildphcldkfpllkvfhq
rmkdrpklkeycekrdaakvpvngngkq

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tu8D (D:)
msykltyfsirglaepirlflvdqdikfiddriakddfssiksqfqfgqlpclydgdqqi
vqsgailrhlarkynlngenemettyidmfcegvrdlhvkytrmiymayetekdpyiksi
lpgelakfekllatrgngrnlilgdkisyadyalfeeldvhqildphcldkfpllkvfhq
rmkdrpklkeycekrdaakvpvngngkq