PDB entry 1tsx

View 1tsx on RCSB PDB site
Description: thymidylate synthase r179e mutant
Class: transferase (methyltransferase)
Keywords: transferase, methyltransferase, nucleotide biosynthesis
Deposited on 1995-12-05, released 1996-03-08
The last revision prior to the SCOP 1.73 freeze date was dated 1996-03-08, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.189
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase
    Species: Lactobacillus casei
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00469 (0-315)
      • engineered (178)
    Domains in SCOP 1.73: d1tsxa_
  • Heterogens: UMP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tsxA (A:)
mleqpyldlakkvldeghfkpdrthtgtysifghqmrfdlskgfpllttkkvpfglikse
llwflhgdtnirfllqhrnhiwdewafekwvksdeyhgpdmtdfghrsqkdpefaavyhe
emakfddrvlhddafaakygdlglvygsqwrawhtskgdtidqlgdvieqikthpysrel
ivsawnpedvptmalppchtlyqfyvndgklslqlyqrsadiflgvpfniasyallthlv
ahecglevgefihtfgdahlyvnhldqikeqlsrtprpaptlqlnpdkhdifdfdmkdik
llnydpypaikapvav