PDB entry 1tpz

View 1tpz on RCSB PDB site
Description: Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases
Class: signaling protein
Keywords: GTPase, Interferon gamma, Crystal structure, dimer, immunology, SIGNALING PROTEIN
Deposited on 2004-06-16, released 2004-09-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.208
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: interferon-inducible GTPase
    Species: Mus musculus [TaxId:10090]
    Gene: IIGP1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9QZ85 (Start-410)
      • cloning artifact (411-414)
    Domains in SCOPe 2.08: d1tpza1, d1tpza2
  • Chain 'B':
    Compound: interferon-inducible GTPase
    Species: Mus musculus [TaxId:10090]
    Gene: IIGP1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9QZ85 (Start-410)
      • cloning artifact (411-414)
    Domains in SCOPe 2.08: d1tpzb1, d1tpzb2
  • Heterogens: MG, GDP, EDO, MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1tpzA (A:)
mgqlfsspksdenndlpssftgyfkkfntgrkiisqeilnlielrmrkgniqltnsaisd
alkeidssvlnvavtgetgsgkssfintlrgigneeegaaktgvvevtmerhpykhpnip
nvvfwdlpgigstnfppdtylekmkfyeydffiiisatrfkkndidiakaismmkkefyf
vrtkvdsditneadgkpqtfdkekvlqdirlncvntfrengiaeppifllsnknvchydf
pvlmdklisdlpiykrhnfmvslpnitdsviekkrqflkqriwlegfaadlvniipsltf
lldsdletlkksmkfyrtvfgvdetslqrlardweievdqveamikspavfkptdeetiq
erlsryiqefclangyllpknsflkeifylkyyfldmvtedaktllkeiclklgrlerph
rd

    Sequence, based on observed residues (ATOM records): (download) 
    >1tpzA (A:)
ndlpssftgyfkkfntgrkiisqeilnlielrmrkgniqltnsaisdalkeidssvlnva
vtgetgsgkssfintlrgigneeegaaktgvvevtmerhpykhpnipnvvfwdlpgigst
nfppdtylekmkfyeydffiiisatrfkkndidiakaismmkkefyfvrtkvdsditnea
dkekvlqdirlncvntfrengiaeppifllsnknvchydfpvlmdklisdlpiykrhnfm
vslpnitdsviekkrqflkqriwlegfaadlvniipsltflldsdletlkksmkfyrtvf
gvdetslqrlardweievdqveamikspavfkptdeetiqerlsryiqefclangyllpk
nsflkeifylkyyfldmvtedaktllkeiclklgr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1tpzB (B:)
mgqlfsspksdenndlpssftgyfkkfntgrkiisqeilnlielrmrkgniqltnsaisd
alkeidssvlnvavtgetgsgkssfintlrgigneeegaaktgvvevtmerhpykhpnip
nvvfwdlpgigstnfppdtylekmkfyeydffiiisatrfkkndidiakaismmkkefyf
vrtkvdsditneadgkpqtfdkekvlqdirlncvntfrengiaeppifllsnknvchydf
pvlmdklisdlpiykrhnfmvslpnitdsviekkrqflkqriwlegfaadlvniipsltf
lldsdletlkksmkfyrtvfgvdetslqrlardweievdqveamikspavfkptdeetiq
erlsryiqefclangyllpknsflkeifylkyyfldmvtedaktllkeiclklgrlerph
rd

    Sequence, based on observed residues (ATOM records): (download) 
    >1tpzB (B:)
ndlpssftgyfkkfntgrkiisqeilnlielrmrkgniqltnsaisdalkeidssvlnva
vtgetgsgkssfintlrgigneeegaaktgvvevtmerhpykhpnipnvvfwdlpgigst
nfppdtylekmkfyeydffiiisatrfkkndidiakaismmkkefyfvrtkvdsditnee
kvlqdirlncvntfrengiaeppifllsnknvchydfpvlmdklisdlpiykrhnfmvsl
pnitdsviekkrqflkqriwlegfaadlvniipsltflldsdletlkksmkfyrtvfgvd
etslqrlardweievdqveamikspavfkptdeetiqerlsryiqefclangyllpknsf
lkeifylkyyfldmvtedaktllkeiclklgr