PDB entry 1tmh

View 1tmh on RCSB PDB site
Description: modular mutagenesis of a tim-barrel enzyme: the crystal structure of a chimeric e. coli tim having the eighth (beta-alpha)-unit replaced by the equivalent unit of chicken tim
Class: isomerase(intramolecular oxidoreductase)
Keywords: isomerase(intramolecular oxidoreductase)
Deposited on 1994-03-22, released 1994-06-22
The last revision prior to the SCOP 1.73 freeze date was dated 1994-07-31, with a file datestamp of 2007-06-04.
Experiment type: -
Resolution: 2.8 Å
R-factor: 0.166
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: triosephosphate isomerase
    Species: ESCHERICHIA COLI
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A858 (0-253)
      • engineered (224)
      • engineered (226)
      • engineered (229)
      • engineered (238-239)
      • engineered (241-242)
      • engineered (244-245)
    Domains in SCOP 1.73: d1tmha_
  • Chain 'B':
    Compound: triosephosphate isomerase
    Species: ESCHERICHIA COLI
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A858 (0-253)
      • engineered (224)
      • engineered (226)
      • engineered (229)
      • engineered (238-239)
      • engineered (241-242)
      • engineered (244-245)
    Domains in SCOP 1.73: d1tmhb_
  • Chain 'C':
    Compound: triosephosphate isomerase
    Species: ESCHERICHIA COLI
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A858 (0-253)
      • engineered (224)
      • engineered (226)
      • engineered (229)
      • engineered (238-239)
      • engineered (241-242)
      • engineered (244-245)
    Domains in SCOP 1.73: d1tmhc_
  • Chain 'D':
    Compound: triosephosphate isomerase
    Species: ESCHERICHIA COLI
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A858 (0-253)
      • engineered (224)
      • engineered (226)
      • engineered (229)
      • engineered (238-239)
      • engineered (241-242)
      • engineered (244-245)
    Domains in SCOP 1.73: d1tmhd_
  • Heterogens: SO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tmhA (A:)
mrhplvmgnwklngsrhmvhelvsnlrkelagvagcavaiappemyidmakreaegshim
lgaqnvdlnlsgaftgetsaamlkdigaqyiiighserrtyhkesdeliakkfavlkeqg
ltpvlcigeteaeneagkteevcarqidavlktqgaaafegaviayepvwaigtgksatp
aqaqavhkfirdhiakvdaniaeqviiqyggsvnasnaaelfaqhdvdgflvggaslkpe
fvdiinaaeaakqa

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tmhB (B:)
mrhplvmgnwklngsrhmvhelvsnlrkelagvagcavaiappemyidmakreaegshim
lgaqnvdlnlsgaftgetsaamlkdigaqyiiighserrtyhkesdeliakkfavlkeqg
ltpvlcigeteaeneagkteevcarqidavlktqgaaafegaviayepvwaigtgksatp
aqaqavhkfirdhiakvdaniaeqviiqyggsvnasnaaelfaqhdvdgflvggaslkpe
fvdiinaaeaakqa

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tmhC (C:)
mrhplvmgnwklngsrhmvhelvsnlrkelagvagcavaiappemyidmakreaegshim
lgaqnvdlnlsgaftgetsaamlkdigaqyiiighserrtyhkesdeliakkfavlkeqg
ltpvlcigeteaeneagkteevcarqidavlktqgaaafegaviayepvwaigtgksatp
aqaqavhkfirdhiakvdaniaeqviiqyggsvnasnaaelfaqhdvdgflvggaslkpe
fvdiinaaeaakqa

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tmhD (D:)
mrhplvmgnwklngsrhmvhelvsnlrkelagvagcavaiappemyidmakreaegshim
lgaqnvdlnlsgaftgetsaamlkdigaqyiiighserrtyhkesdeliakkfavlkeqg
ltpvlcigeteaeneagkteevcarqidavlktqgaaafegaviayepvwaigtgksatp
aqaqavhkfirdhiakvdaniaeqviiqyggsvnasnaaelfaqhdvdgflvggaslkpe
fvdiinaaeaakqa