PDB entry 1tjj

View 1tjj on RCSB PDB site
Description: Human GM2 Activator Protein PAF complex
Class: signaling protein
Keywords: platelet activating factor, lipid binding pocket, beta-cup topology, protein dynamics, SIGNALING PROTEIN
Deposited on 2004-06-04, released 2004-12-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-10-16, with a file datestamp of 2013-10-11.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.189
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ganglioside GM2 activator
    Species: Homo sapiens [TaxId:9606]
    Gene: GM2A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17900 (2-163)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d1tjja1, d1tjja2
  • Chain 'B':
    Compound: Ganglioside GM2 activator
    Species: Homo sapiens [TaxId:9606]
    Gene: GM2A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17900 (2-163)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d1tjjb1, d1tjjb2
  • Chain 'C':
    Compound: Ganglioside GM2 activator
    Species: Homo sapiens [TaxId:9606]
    Gene: GM2A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17900 (2-163)
      • expression tag (1)
    Domains in SCOPe 2.08: d1tjjc1, d1tjjc2
  • Heterogens: ACT, CL, EPE, PFS, LPE, DAO, IPA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tjjA (A:)
hmssfswdncdegkdpavirsltlepdpivvpgnvtlsvvgstsvplssplkvdlvleke
vaglwikipctdyigsctfehfcdvldmliptgepcpeplrtyglpchcpfkegtyslpk
sefvvpdlelpswlttgnyriesvlsssgkrlgcikiaaslkgi

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tjjB (B:)
hmssfswdncdegkdpavirsltlepdpivvpgnvtlsvvgstsvplssplkvdlvleke
vaglwikipctdyigsctfehfcdvldmliptgepcpeplrtyglpchcpfkegtyslpk
sefvvpdlelpswlttgnyriesvlsssgkrlgcikiaaslkgi

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1tjjC (C:)
hmssfswdncdegkdpavirsltlepdpivvpgnvtlsvvgstsvplssplkvdlvleke
vaglwikipctdyigsctfehfcdvldmliptgepcpeplrtyglpchcpfkegtyslpk
sefvvpdlelpswlttgnyriesvlsssgkrlgcikiaaslkgi

    Sequence, based on observed residues (ATOM records): (download) 
    >1tjjC (C:)
mssfswdncdegkdpavirsltlepdpivvpgnvtlsvvgstsvplssplkvdlvlekev
aglwikipctdyigsctfehfcdvldmliptgepcpeplrtyglpchcpfkegtyslpks
efvvpdlelpswlttgnyriesvlsssgkrlgcikiaaslkgi