PDB entry 1tjh

View 1tjh on RCSB PDB site
Description: Crystal Structure of the broadly neutralizing anti-HIV-1 antibody 2F5 in complex with a gp41 11mer epitope
Class: Viral protein/Immune system
Keywords: 2F5, antibody, gp41, HIV-1, neutralizing, membrane-proximal, Viral protein/Immune system COMPLEX
Deposited on 2004-06-04, released 2004-10-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.2
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: anti-HIV-1 antibody 2F5 Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1TJH (0-236)
    Domains in SCOPe 2.08: d1tjhh1, d1tjhh2
  • Chain 'L':
    Compound: anti-HIV-1 antibody 2F5 Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1TJH (0-213)
    Domains in SCOPe 2.08: d1tjhl1, d1tjhl2
  • Chain 'P':
    Compound: envelope glycoprotein gp41
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Heterogens: EDO, IPA, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tjhH (H:)
ritlkesgpplvkptqtltltcsfsgfslsdfgvgvgwirqppgkalewlaiiysdddkr
yspslntrltitkdtsknqvvlvmtrvspvdtatyfcahrrgpttlfgvpiargpvnamd
vwgqgitvtisststkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgalts
gvhtfpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdk

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tjhL (L:)
alqltqspsslsasvgdrititcrasqgvtsalawyrqkpgsppqlliydasslesgvps
rfsgsgsgteftltistlrpedfatyycqqlhfyphtfgggtrvdvrrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

  • Chain 'P':
    No sequence available.