SCOPe 2.07: Structural Classification of Proteins

PDB entry 1thr

View 1thr on RCSB PDB site
Description: structures of thrombin complexes with a designed and a natural exosite inhibitor
Class: hydrolase(serine proteinase)
Keywords: hydrolase(serine proteinase)
Deposited on 1993-06-16, released 1994-01-31
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-07.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.155
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

Chain 'H':
Compound: alpha-thrombin (large subunit)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P00734 (0-258)
Domains in SCOPe 2.07: d1thr.1
Chain 'I':
Compound: hirullin
Species: Hirudinaria manillensis [TaxId:6419]
Database cross-references and differences (RAF-indexed):
- Uniprot P26631 (0-12)
Chain 'L':
Compound: alpha-thrombin (small subunit)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P00734 (8-21)
Domains in SCOPe 2.07: d1thr.1
Heterogens: HOH

PDB Chain Sequences:

Chain 'H':
Sequence, based on SEQRES records: (download)

>1thrH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge

Sequence, based on observed residues (ATOM records): (download)

>1thrH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketgqpsvlqvvnlpiverpvckdstriritdnmfc
agykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlk
kwiqkvidqfge

Chain 'I':
No sequence available.
Chain 'L':
Sequence, based on SEQRES records: (download)
```
>1thrL (L:)
tfgsgeadcglrplfekksledkterellesyidgr
```
Sequence, based on observed residues (ATOM records): (download)
```
>1thrL (L:)
adcglrplfekksledkterellesyi
```