PDB entry 1tee

View 1tee on RCSB PDB site
Description: Crystal structure of C205F mutant of PKS18 from Mycobacterium tuberculosis
Class: transferase
Keywords: thiolase fold, substrate binding tunnel
Deposited on 2004-05-25, released 2004-08-03
The last revision prior to the SCOP 1.73 freeze date was dated 2004-09-21, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.221
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: pks18
    Species: Mycobacterium tuberculosis
    Gene: pks18
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7D8I1 (Start-392)
      • engineered (204)
    Domains in SCOP 1.73: d1teea_
  • Chain 'B':
    Compound: pks18
    Species: Mycobacterium tuberculosis
    Gene: pks18
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7D8I1 (Start-392)
      • engineered (204)
    Domains in SCOP 1.73: d1teeb_
  • Chain 'C':
    Compound: pks18
    Species: Mycobacterium tuberculosis
    Gene: pks18
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7D8I1 (Start-392)
      • engineered (204)
    Domains in SCOP 1.73: d1teec_
  • Chain 'D':
    Compound: pks18
    Species: Mycobacterium tuberculosis
    Gene: pks18
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7D8I1 (Start-392)
      • engineered (204)
    Domains in SCOP 1.73: d1teed_

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1teeA (A:)
mnvsaesgaprragqrhevglaqlppappttvavieglatgtprrvvnqsdaadrvaelf
ldpgqreriprvyqksrittrrmavdpldakfdvfrrepatirdrmhlfyehavplavdv
skralaglpyraaeigllvlatstgfiapgvdvaivkelglspsisrvvvnfmgcaaamn
algtatnyvrahpamkalvvcielfsvnavfaddindvvihslfgdgcaalvigasqvqe
klepgkvvvrssfsqlldntedgivlgvnhngitcelsenlpgyifsgvapvvtemlwdn
glqisdidlwaihpggpkiieqsvrslgisaelaaqswdvlarfgnmlsvslifvletmv
qqaesakaistgvafafgpgvtvegmlfdiirr

    Sequence, based on observed residues (ATOM records): (download) 
    >1teeA (A:)
aqlppappttvavieglatgtprrvvnqsdaadrvaelgqreriprvyqksrittrrmav
dpldakfdvfrrepatirdrmhlfyehavplavdvskralaglpyraaeigllvlatstg
fiapgvdvaivkelglspsisrvvvnfmgcaaamnalgtatnyvrahpamkalvvcielf
svnavfaddindvvihslfgdgcaalvigasqvqeklepgkvvvrssfsqlldntedgiv
lgvnhngitcelsenlpgyifsgvapvvtemlwdnglqisdidlwaihpggpkiieqsvr
slgisaelaaqswdvlarfgnmlsvslifvletmvqqaesakaistgvafafgpgvtveg
mlfdiirr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1teeB (B:)
mnvsaesgaprragqrhevglaqlppappttvavieglatgtprrvvnqsdaadrvaelf
ldpgqreriprvyqksrittrrmavdpldakfdvfrrepatirdrmhlfyehavplavdv
skralaglpyraaeigllvlatstgfiapgvdvaivkelglspsisrvvvnfmgcaaamn
algtatnyvrahpamkalvvcielfsvnavfaddindvvihslfgdgcaalvigasqvqe
klepgkvvvrssfsqlldntedgivlgvnhngitcelsenlpgyifsgvapvvtemlwdn
glqisdidlwaihpggpkiieqsvrslgisaelaaqswdvlarfgnmlsvslifvletmv
qqaesakaistgvafafgpgvtvegmlfdiirr

    Sequence, based on observed residues (ATOM records): (download) 
    >1teeB (B:)
tvavieglatgtprrvvnqsdaadrvaelgqreriprvyqksrittrrmavdpldakfdv
frrepatirdrmhlfyehavplavdvskralaglpyraaeigllvlatstgfiapgvdva
ivkelglspsisrvvvnfmgcaaamnalgtatnyvrahpamkalvvcielfsvnavfadd
indvvihslfgdgcaalvigasqvqeklepgkvvvrssfsqlldntedgivlgvnhngit
celsenlpgyifsgvapvvtemlwdnglqisdidlwaihpggpkiieqsvrslgisaela
aqswdvlarfgnmlsvslifvletmvqqaesakaistgvafafgpgvtvegmlfdiirr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1teeC (C:)
mnvsaesgaprragqrhevglaqlppappttvavieglatgtprrvvnqsdaadrvaelf
ldpgqreriprvyqksrittrrmavdpldakfdvfrrepatirdrmhlfyehavplavdv
skralaglpyraaeigllvlatstgfiapgvdvaivkelglspsisrvvvnfmgcaaamn
algtatnyvrahpamkalvvcielfsvnavfaddindvvihslfgdgcaalvigasqvqe
klepgkvvvrssfsqlldntedgivlgvnhngitcelsenlpgyifsgvapvvtemlwdn
glqisdidlwaihpggpkiieqsvrslgisaelaaqswdvlarfgnmlsvslifvletmv
qqaesakaistgvafafgpgvtvegmlfdiirr

    Sequence, based on observed residues (ATOM records): (download) 
    >1teeC (C:)
aqlppappttvavieglatgtprrvvnqsdaadrvaelgqreriprvyqksrittrrmav
dpldakfdvfrrepatirdrmhlfyehavplavdvskralaglpyraaeigllvlatstg
fiapgvdvaivkelglspsisrvvvnfmgcaaamnalgtatnyvrahpamkalvvcielf
svnavfaddindvvihslfgdgcaalvigasqvqeklepgkvvvrssfsqlldntedgiv
lgvnhngitcelsenlpgyifsgvapvvtemlwdnglqisdidlwaihpggpkiieqsvr
slgisaelaaqswdvlarfgnmlsvslifvletmvqqaesakaistgvafafgpgvtveg
mlfdiirr

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1teeD (D:)
mnvsaesgaprragqrhevglaqlppappttvavieglatgtprrvvnqsdaadrvaelf
ldpgqreriprvyqksrittrrmavdpldakfdvfrrepatirdrmhlfyehavplavdv
skralaglpyraaeigllvlatstgfiapgvdvaivkelglspsisrvvvnfmgcaaamn
algtatnyvrahpamkalvvcielfsvnavfaddindvvihslfgdgcaalvigasqvqe
klepgkvvvrssfsqlldntedgivlgvnhngitcelsenlpgyifsgvapvvtemlwdn
glqisdidlwaihpggpkiieqsvrslgisaelaaqswdvlarfgnmlsvslifvletmv
qqaesakaistgvafafgpgvtvegmlfdiirr

    Sequence, based on observed residues (ATOM records): (download) 
    >1teeD (D:)
tvavieglatgtprrvvnqsdaadrvaelgqreriprvyqksrittrrmavdpldakfdv
frrepatirdrmhlfyehavplavdvskralaglpyraaeigllvlatstgfiapgvdva
ivkelglspsisrvvvnfmgcaaamnalgtatnyvrahpamkalvvcielfsvnavfadd
indvvihslfgdgcaalvigasqvqeklepgkvvvrssfsqlldntedgivlgvnhngit
celsenlpgyifsgvapvvtemlwdnglqisdidlwaihpggpkiieqsvrslgisaela
aqswdvlarfgnmlsvslifvletmvqqaesakaistgvafafgpgvtvegmlfdiirr