PDB entry 1tdw

View 1tdw on RCSB PDB site
Description: Crystal structure of double truncated human phenylalanine hydroxylase BH4-responsive PKU mutant A313T.
Class: oxidoreductase
Keywords: phenylalanine catabolism, OXIDOREDUCTASE
Deposited on 2004-05-24, released 2004-11-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phenylalanine-4-hydroxylase
    Species: Homo sapiens [TaxId:9606]
    Gene: PAH
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00439 (0-307)
      • engineered (196)
    Domains in SCOPe 2.08: d1tdwa_
  • Heterogens: FE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1tdwA (A:)
    tvpwfprtiqeldrfanqilsygaeldadhpgfkdpvyrarrkqfadiaynyrhgqpipr
    veymeeekktwgtvfktlkslykthacyeynhifpllekycgfhednipqledvsqflqt
    ctgfrlrpvagllssrdflgglafrvfhctqyirhgskpmytpepdichellghvplfsd
    rsfaqfsqeiglaslgtpdeyieklatiywftvefglckqgdsikaygagllssfgelqy
    clsekpkllplelektaiqnytvtefqplyyvaesfndakekvrnfaatiprpfsvrydp
    ytqrievl