PDB entry 1tcv

View 1tcv on RCSB PDB site
Description: Crystal Structure of the Purine Nucleoside Phosphorylase from Schistosoma mansoni in complex with Non-detergent Sulfobetaine 195 and acetate
Class: transferase
Keywords: Purine Nucleoside Phosphorylase, TRANSFERASE
Deposited on 2004-05-21, released 2005-05-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.18
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: purine-nucleoside phosphorylase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: SmPNP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1tcva_
  • Chain 'B':
    Compound: purine-nucleoside phosphorylase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: SmPNP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1tcvb_
  • Chain 'C':
    Compound: purine-nucleoside phosphorylase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: SmPNP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1tcvc_
  • Heterogens: ACT, NDS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1tcvA (A:)
mhesvtanienvkkvahhiqkltsivpeigiicgsglgkladgvkdkitipytkipnfpq
tsvvghsgnlifgtlsgrkvvvmqgrfhmyegysndtvalpirvmkllgvkilmvsnaag
glnrslklgdfvilkdhiylpglglnnilvgpnqeafgtrfpalsnaydrdlrklavqva
eengfgnlvhqgvyvmnggpcyetpaectmllnmgcdvvgmstipevviarhcgiqvfav
slvtnisvldvesdlkpnheevlatgaqraelmqswfekiieklpkd

    Sequence, based on observed residues (ATOM records): (download) 
    >1tcvA (A:)
esvtanienvkkvahhiqkltsivpeigiicgsglgkladgvkdkitipytkipnfpqts
hsgnlifgtlsgrkvvvmqgrfhmyegysndtvalpirvmkllgvkilmvsnaagglnrs
lklgdfvilkdhiylpglglnnilvgpnqeafgtrfpalsnaydrdlrklavqvaeengf
gnlvhqgvyvmnggpcyetpaectmllnmgcdvvgmstipevviarhcgiqvfavslvtn
isvldvesdgaqraelmqswfekiieklpkd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1tcvB (B:)
mhesvtanienvkkvahhiqkltsivpeigiicgsglgkladgvkdkitipytkipnfpq
tsvvghsgnlifgtlsgrkvvvmqgrfhmyegysndtvalpirvmkllgvkilmvsnaag
glnrslklgdfvilkdhiylpglglnnilvgpnqeafgtrfpalsnaydrdlrklavqva
eengfgnlvhqgvyvmnggpcyetpaectmllnmgcdvvgmstipevviarhcgiqvfav
slvtnisvldvesdlkpnheevlatgaqraelmqswfekiieklpkd

    Sequence, based on observed residues (ATOM records): (download) 
    >1tcvB (B:)
svtanienvkkvahhiqkltsivpeigiicgsglgkladgvkdkitipytkipnfpqtss
gnlifgtlsgrkvvvmqgrfhmyegysndtvalpirvmkllgvkilmvsnaagglnrslk
lgdfvilkdhiylpglglnnilvgpnqeafgtrfpalsnaydrdlrklavqvaeengfgn
lvhqgvyvmnggpcyetpaectmllnmgcdvvgmstipevviarhcgiqvfavslvtnis
vldveseevlatgaqraelmqswfekiieklpkd

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1tcvC (C:)
mhesvtanienvkkvahhiqkltsivpeigiicgsglgkladgvkdkitipytkipnfpq
tsvvghsgnlifgtlsgrkvvvmqgrfhmyegysndtvalpirvmkllgvkilmvsnaag
glnrslklgdfvilkdhiylpglglnnilvgpnqeafgtrfpalsnaydrdlrklavqva
eengfgnlvhqgvyvmnggpcyetpaectmllnmgcdvvgmstipevviarhcgiqvfav
slvtnisvldvesdlkpnheevlatgaqraelmqswfekiieklpkd

    Sequence, based on observed residues (ATOM records): (download) 
    >1tcvC (C:)
svtanienvkkvahhiqkltsivpeigiicgsglgkladgvkdkitipytkipnfpqths
gnlifgtlsgrkvvvmqgrfhmyegysndtvalpirvmkllgvkilmvsnaagglnrslk
lgdfvilkdhiylpglglnnilvgpnqeafgtrfpalsnaydrdlrklavqvaeengfgn
lvhqgvyvmnggpcyetpaectmllnmgcdvvgmstipevviarhcgiqvfavslvtnis
vldvesdlkpnheevlatgaqraelmqswfekiieklpkd