PDB entry 1tbw

View 1tbw on RCSB PDB site
Description: Ligand Induced Conformational Shift in the N-terminal Domain of GRP94, Open Conformation
Class: chaperone
Keywords: GRP94, HSP90, AMP, Bergrat, Chaperone, Endoplasmic reticulum
Deposited on 2004-05-20, released 2004-08-24
The last revision prior to the SCOP 1.73 freeze date was dated 2004-11-02, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: 0.22
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Endoplasmin
    Species: Canis familiaris
    Gene: TRA1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41148 (Start-221)
      • see remark 999 (225)
    • Uniprot P41148 (226-235)
    Domains in SCOP 1.73: d1tbwa_
  • Chain 'B':
    Compound: Endoplasmin
    Species: Canis familiaris
    Gene: TRA1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41148
      • see remark 999 (225)
    • Uniprot P41148 (226-235)
    Domains in SCOP 1.73: d1tbwb_
  • Heterogens: MG, AMP, PG4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1tbwA (A:)
gshmlreksekfafqaevnrmmkliinslyknkeiflrelisnasdaldkirlisltden
alagneeltvkikcdkeknllhvtdtgvgmtreelvknlgtiaksgtseflnkmteaqed
gqstseligqfgvgfysaflvadkvivtskhnndtqhiwesdsnefsviadprgntlgrg
ttitlvlkeeasdyleldtiknlvkkysqfinfpiyvwssktggggktvwdwelmn

    Sequence, based on observed residues (ATOM records): (download) 
    >1tbwA (A:)
fafqaevnrmmkliinslyknkeiflrelisnasdaldkirlisltdenalagneeltvk
ikcdkeknllhvtdtgvgmtreelvknlgtiaksgtseflnkmteaqedgqstseligqf
gvgfysaflvadkvivtskhnndtqhiwesdsnefsviadprgntlgrgttitlvlkeea
sdyleldtiknlvkkysqfinfpiyvwssktgktvwdwelmn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1tbwB (B:)
gshmlreksekfafqaevnrmmkliinslyknkeiflrelisnasdaldkirlisltden
alagneeltvkikcdkeknllhvtdtgvgmtreelvknlgtiaksgtseflnkmteaqed
gqstseligqfgvgfysaflvadkvivtskhnndtqhiwesdsnefsviadprgntlgrg
ttitlvlkeeasdyleldtiknlvkkysqfinfpiyvwssktggggktvwdwelmn

    Sequence, based on observed residues (ATOM records): (download) 
    >1tbwB (B:)
qaevnrmmkliinslyknkeiflrelisnasdaldkirlisltdenalagneeltvkikc
dkeknllhvtdtgvgmtreelvknlstseligqfgvgfysaflvadkvivtskhnndtqh
iwesdsnefsviadprgntlgrgttitlvlkeeasdyleldtiknlvkkysqfinfpiyv
wsskgktvwdwelmn