PDB entry 1tbm
View 1tbm on RCSB PDB site
Description: Crystal structure of phosphodiesterase 9 shows orientation variation of inhibitor IBMX binding
Class: Hydrolase
Keywords: PDE, IBMX, inhibitor binding, crystal structure
Deposited on
2004-05-20, released
2004-07-06
The last revision prior to the SCOPe 2.08 freeze date was dated
2006-06-27, with a file datestamp of
2007-06-01.
Experiment type: XRAY
Resolution: 2.23 Å
R-factor: 0.215
AEROSPACI score: 0.38
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: cGMP phosphodiesterase A2
Species: HOMO SAPIENS
Gene: pde9a2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1tbma_ - Chain 'B':
Compound: cGMP phosphodiesterase A2
Species: HOMO SAPIENS
Gene: pde9a2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1tbmb_ - Heterogens: ZN, MG, IBM, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1tbmA (A:)
ptypkyllspetiealrkptfdvwlwepnemlsclehmyhdlglvrdfsinpvtlrrwlf
cvhdnyrnnpfhnfrhcfcvaqmmysmvwlcslqekfsqtdililmtaaichdldhpgyn
ntyqinartelavryndisplenhhcavafqilaepecnifsnippdgfkqirqgmitli
latdmarhaeimdsfkekmenfdysneehmtllkmilikccdisnevrpmevaepwvdcl
leeyfmqsdrekseglpvapfmdrdkvtkataqigfikfvlipmfetvtklfpmveeiml
qplwesrdryeelkriddamkelqkk
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1tbmB (B:)
ptypkyllspetiealrkptfdvwlwepnemlsclehmyhdlglvrdfsinpvtlrrwlf
cvhdnyrnnpfhnfrhcfcvaqmmysmvwlcslqekfsqtdililmtaaichdldhpgyn
ntyqinartelavryndisplenhhcavafqilaepecnifsnippdgfkqirqgmitli
latdmarhaeimdsfkekmenfdysneehmtllkmilikccdisnevrpmevaepwvdcl
leeyfmqsdrekseglpvapfmdrdkvtkataqigfikfvlipmfetvtklfpmveeiml
qplwesrdryeelkriddamkelqkk