PDB entry 1ta2
View 1ta2 on RCSB PDB site
Description: Crystal structure of thrombin in complex with compound 1
Class: hydrolase/hydrolase inhibitor
Keywords: thrombin inhibitor complex, BLOOD CLOTTING, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
Deposited on
2004-05-19, released
2004-06-08
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-10-11, with a file datestamp of
2017-10-06.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: thrombin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1ta2a_ - Chain 'B':
Compound: hirudin
Species: Hirudo medicinalis [TaxId:6421]
Database cross-references and differences (RAF-indexed):
- Uniprot P28504 (0-10)
- conflict (7)
- conflict (10)
- Heterogens: 176, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1ta2A (A:)
dcglrplfekksledkterellesyidgrivegsdaeigmspwqvmlfrkspqellcgas
lisdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihpryn
wrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwtan
vgkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvm
kspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfg
Sequence, based on observed residues (ATOM records): (download)
>1ta2A (A:)
dcglrplfekksledkterellesyiivegsdaeigmspwqvmlfrkspqellcgaslis
drwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihprynwre
nldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlkegqpsvlqv
vnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqm
givswgegcdrdgkygfythvfrlkkwiqkvidqfg
- Chain 'B':
No sequence available.