PDB entry 1t8w

View 1t8w on RCSB PDB site
Description: Crystal Structure of E. coli AMP Nucleosidase
Class: hydrolase
Keywords: alpha-beta-alpha sandwich, alpha-beta fold, hydrolase
Deposited on 2004-05-13, released 2004-08-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.223
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: AMP nucleosidase
    Species: Escherichia coli [TaxId:562]
    Gene: AMN, B1982, Z3139, ECS2779
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15272 (Start-483)
      • modified residue (137)
      • modified residue (259)
      • modified residue (301)
      • modified residue (403)
    Domains in SCOPe 2.08: d1t8wa_
  • Chain 'B':
    Compound: AMP nucleosidase
    Species: Escherichia coli [TaxId:562]
    Gene: AMN, B1982, Z3139, ECS2779
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15272 (Start-483)
      • modified residue (137)
      • modified residue (259)
      • modified residue (301)
      • modified residue (403)
    Domains in SCOPe 2.08: d1t8wb_
  • Chain 'C':
    Compound: AMP nucleosidase
    Species: Escherichia coli [TaxId:562]
    Gene: AMN, B1982, Z3139, ECS2779
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15272 (Start-483)
      • modified residue (137)
      • modified residue (259)
      • modified residue (301)
      • modified residue (403)
    Domains in SCOPe 2.08: d1t8wc_
  • Chain 'D':
    Compound: AMP nucleosidase
    Species: Escherichia coli [TaxId:562]
    Gene: AMN, B1982, Z3139, ECS2779
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15272 (Start-483)
      • modified residue (137)
      • modified residue (259)
      • modified residue (301)
      • modified residue (403)
    Domains in SCOPe 2.08: d1t8wd_
  • Chain 'E':
    Compound: AMP nucleosidase
    Species: Escherichia coli [TaxId:562]
    Gene: AMN, B1982, Z3139, ECS2779
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15272 (Start-483)
      • modified residue (137)
      • modified residue (259)
      • modified residue (301)
      • modified residue (403)
    Domains in SCOPe 2.08: d1t8we_
  • Chain 'F':
    Compound: AMP nucleosidase
    Species: Escherichia coli [TaxId:562]
    Gene: AMN, B1982, Z3139, ECS2779
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15272 (Start-483)
      • modified residue (137)
      • modified residue (259)
      • modified residue (301)
      • modified residue (403)
    Domains in SCOPe 2.08: d1t8wf_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1t8wA (A:)
mnnkgsgltpaqaldkldalyeqsvvalrnaignyitsgelpdenarkqglfvypsltvt
wdgsttnppktrafgrfthagsytttitrptlfrsylneqltllyqdygahisvqpsqhe
ipypyvidgseltldrsmsagltryfpttelaqigdetadgiyhptefsplshfdarrvd
fslarlrhytgtpvehfqpfvlftnytryvdefvrwgcsqildpdspyialscaggnwit
aeteapeeaisdlawkkhqmpawhlitadgqgitlvnigvgpsnakticdhlavlrpdvw
lmighcgglresqaigdyvlahaylrddhvldavlppdipipsiaevqralydatklvsg
rpgeevkqrlrtgtvvttddrnwelrysasalrfnlsravaidmesatiaaqgyrfrvpy
gtllcvsdkplhgeiklpgqanrfyegaisehlqigiraidllraegdrlhsrklrtfne
ppfr

    Sequence, based on observed residues (ATOM records): (download) 
    >1t8wA (A:)
ltpaqaldkldalyeqsvvalrnaignyitsgelpdenarkqglfvypsltvtwdgsttn
ppktrafgrfthagsytttitrptlfrsylneqltllyqdygahisvqpsqheipypyvi
dgseltldrsmsagltryfpttelfsplshfdarrvdfslarlrhytgtpvehfqpfvlf
tnytryvdefvrwgcsqildpdspyialscaggnwitaeteapeeaisdlawkkhqmpaw
hlitadgqgitlvnigvgpsnakticdhlavlrpdvwlmighcgglresqaigdyvlaha
ylrddhvldavlppdipipsiaevqralydatklvsgrpgeevkqrlrtgtvvttddrnw
elrysasalrfnlsravaidmesatiaaqgyrfrvpygtllcvsdkplhgeiklpgqanr
fyegaisehlqigiraidllraegdrlhsrklrtfneppfr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1t8wB (B:)
mnnkgsgltpaqaldkldalyeqsvvalrnaignyitsgelpdenarkqglfvypsltvt
wdgsttnppktrafgrfthagsytttitrptlfrsylneqltllyqdygahisvqpsqhe
ipypyvidgseltldrsmsagltryfpttelaqigdetadgiyhptefsplshfdarrvd
fslarlrhytgtpvehfqpfvlftnytryvdefvrwgcsqildpdspyialscaggnwit
aeteapeeaisdlawkkhqmpawhlitadgqgitlvnigvgpsnakticdhlavlrpdvw
lmighcgglresqaigdyvlahaylrddhvldavlppdipipsiaevqralydatklvsg
rpgeevkqrlrtgtvvttddrnwelrysasalrfnlsravaidmesatiaaqgyrfrvpy
gtllcvsdkplhgeiklpgqanrfyegaisehlqigiraidllraegdrlhsrklrtfne
ppfr

    Sequence, based on observed residues (ATOM records): (download) 
    >1t8wB (B:)
ltpaqaldkldalyeqsvvalrnaignyitsgelpdenarkqglfvypsltvtwdgsttn
ppktrafgrfthagsytttitrptlfrsylneqltllyqdygahisvqpsqheipypyvi
dgseltldrsmsagltryfpttelfsplshfdarrvdfslarlrhytgtpvehfqpfvlf
tnytryvdefvrwgcsqildpdspyialscaggnwitaeteapeeaisdlawkkhqmpaw
hlitadgqgitlvnigvgpsnakticdhlavlrpdvwlmighcgglresqaigdyvlaha
ylrddhvldavlppdipipsiaevqralydatklvsgrpgeevkqrlrtgtvvttddrnw
elrysasalrfnlsravaidmesatiaaqgyrfrvpygtllcvsdkplhgeiklpgqanr
fyegaisehlqigiraidllraegdrlhsrklrtfneppfr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1t8wC (C:)
mnnkgsgltpaqaldkldalyeqsvvalrnaignyitsgelpdenarkqglfvypsltvt
wdgsttnppktrafgrfthagsytttitrptlfrsylneqltllyqdygahisvqpsqhe
ipypyvidgseltldrsmsagltryfpttelaqigdetadgiyhptefsplshfdarrvd
fslarlrhytgtpvehfqpfvlftnytryvdefvrwgcsqildpdspyialscaggnwit
aeteapeeaisdlawkkhqmpawhlitadgqgitlvnigvgpsnakticdhlavlrpdvw
lmighcgglresqaigdyvlahaylrddhvldavlppdipipsiaevqralydatklvsg
rpgeevkqrlrtgtvvttddrnwelrysasalrfnlsravaidmesatiaaqgyrfrvpy
gtllcvsdkplhgeiklpgqanrfyegaisehlqigiraidllraegdrlhsrklrtfne
ppfr

    Sequence, based on observed residues (ATOM records): (download) 
    >1t8wC (C:)
ltpaqaldkldalyeqsvvalrnaignyitsgelpdenarkqglfvypsltvtwdgsttn
ppktrafgrfthagsytttitrptlfrsylneqltllyqdygahisvqpsqheipypyvi
dgseltldrsmsagltryfpttelfsplshfdarrvdfslarlrhytgtpvehfqpfvlf
tnytryvdefvrwgcsqildpdspyialscaggnwitaeteapeeaisdlawkkhqmpaw
hlitadgqgitlvnigvgpsnakticdhlavlrpdvwlmighcgglresqaigdyvlaha
ylrddhvldavlppdipipsiaevqralydatklvsgrpgeevkqrlrtgtvvttddrnw
elrysasalrfnlsravaidmesatiaaqgyrfrvpygtllcvsdkplhgeiklpgqanr
fyegaisehlqigiraidllraegdrlhsrklrtfneppfr

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1t8wD (D:)
mnnkgsgltpaqaldkldalyeqsvvalrnaignyitsgelpdenarkqglfvypsltvt
wdgsttnppktrafgrfthagsytttitrptlfrsylneqltllyqdygahisvqpsqhe
ipypyvidgseltldrsmsagltryfpttelaqigdetadgiyhptefsplshfdarrvd
fslarlrhytgtpvehfqpfvlftnytryvdefvrwgcsqildpdspyialscaggnwit
aeteapeeaisdlawkkhqmpawhlitadgqgitlvnigvgpsnakticdhlavlrpdvw
lmighcgglresqaigdyvlahaylrddhvldavlppdipipsiaevqralydatklvsg
rpgeevkqrlrtgtvvttddrnwelrysasalrfnlsravaidmesatiaaqgyrfrvpy
gtllcvsdkplhgeiklpgqanrfyegaisehlqigiraidllraegdrlhsrklrtfne
ppfr

    Sequence, based on observed residues (ATOM records): (download) 
    >1t8wD (D:)
ltpaqaldkldalyeqsvvalrnaignyitsgelpdenarkqglfvypsltvtwdgsttn
ppktrafgrfthagsytttitrptlfrsylneqltllyqdygahisvqpsqheipypyvi
dgseltldrsmsagltryfpttelfsplshfdarrvdfslarlrhytgtpvehfqpfvlf
tnytryvdefvrwgcsqildpdspyialscaggnwitaeteapeeaisdlawkkhqmpaw
hlitadgqgitlvnigvgpsnakticdhlavlrpdvwlmighcgglresqaigdyvlaha
ylrddhvldavlppdipipsiaevqralydatklvsgrpgeevkqrlrtgtvvttddrnw
elrysasalrfnlsravaidmesatiaaqgyrfrvpygtllcvsdkplhgeiklpgqanr
fyegaisehlqigiraidllraegdrlhsrklrtfneppfr

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1t8wE (E:)
mnnkgsgltpaqaldkldalyeqsvvalrnaignyitsgelpdenarkqglfvypsltvt
wdgsttnppktrafgrfthagsytttitrptlfrsylneqltllyqdygahisvqpsqhe
ipypyvidgseltldrsmsagltryfpttelaqigdetadgiyhptefsplshfdarrvd
fslarlrhytgtpvehfqpfvlftnytryvdefvrwgcsqildpdspyialscaggnwit
aeteapeeaisdlawkkhqmpawhlitadgqgitlvnigvgpsnakticdhlavlrpdvw
lmighcgglresqaigdyvlahaylrddhvldavlppdipipsiaevqralydatklvsg
rpgeevkqrlrtgtvvttddrnwelrysasalrfnlsravaidmesatiaaqgyrfrvpy
gtllcvsdkplhgeiklpgqanrfyegaisehlqigiraidllraegdrlhsrklrtfne
ppfr

    Sequence, based on observed residues (ATOM records): (download) 
    >1t8wE (E:)
ltpaqaldkldalyeqsvvalrnaignyitsgelpdenarkqglfvypsltvtwdgsttn
ppktrafgrfthagsytttitrptlfrsylneqltllyqdygahisvqpsqheipypyvi
dgseltldrsmsagltryfpttelfsplshfdarrvdfslarlrhytgtpvehfqpfvlf
tnytryvdefvrwgcsqildpdspyialscaggnwitaeteapeeaisdlawkkhqmpaw
hlitadgqgitlvnigvgpsnakticdhlavlrpdvwlmighcgglresqaigdyvlaha
ylrddhvldavlppdipipsiaevqralydatklvsgrpgeevkqrlrtgtvvttddrnw
elrysasalrfnlsravaidmesatiaaqgyrfrvpygtllcvsdkplhgeiklpgqanr
fyegaisehlqigiraidllraegdrlhsrklrtfneppfr

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1t8wF (F:)
mnnkgsgltpaqaldkldalyeqsvvalrnaignyitsgelpdenarkqglfvypsltvt
wdgsttnppktrafgrfthagsytttitrptlfrsylneqltllyqdygahisvqpsqhe
ipypyvidgseltldrsmsagltryfpttelaqigdetadgiyhptefsplshfdarrvd
fslarlrhytgtpvehfqpfvlftnytryvdefvrwgcsqildpdspyialscaggnwit
aeteapeeaisdlawkkhqmpawhlitadgqgitlvnigvgpsnakticdhlavlrpdvw
lmighcgglresqaigdyvlahaylrddhvldavlppdipipsiaevqralydatklvsg
rpgeevkqrlrtgtvvttddrnwelrysasalrfnlsravaidmesatiaaqgyrfrvpy
gtllcvsdkplhgeiklpgqanrfyegaisehlqigiraidllraegdrlhsrklrtfne
ppfr

    Sequence, based on observed residues (ATOM records): (download) 
    >1t8wF (F:)
ltpaqaldkldalyeqsvvalrnaignyitsgelpdenarkqglfvypsltvtwdgsttn
ppktrafgrfthagsytttitrptlfrsylneqltllyqdygahisvqpsqheipypyvi
dgseltldrsmsagltryfpttelfsplshfdarrvdfslarlrhytgtpvehfqpfvlf
tnytryvdefvrwgcsqildpdspyialscaggnwitaeteapeeaisdlawkkhqmpaw
hlitadgqgitlvnigvgpsnakticdhlavlrpdvwlmighcgglresqaigdyvlaha
ylrddhvldavlppdipipsiaevqralydatklvsgrpgeevkqrlrtgtvvttddrnw
elrysasalrfnlsravaidmesatiaaqgyrfrvpygtllcvsdkplhgeiklpgqanr
fyegaisehlqigiraidllraegdrlhsrklrtfneppfr