PDB entry 1t76

View 1t76 on RCSB PDB site
Description: Crystal structure of the androgen receptor ligand binding domain in complex with a WxxVW motif
Class: hormone/growth factor receptor
Keywords: nuclear receptor, transcription factor, ligand binding domain, AF-2, androgen, testosterone, DHT, alpha-helical sandwich
Deposited on 2004-05-08, released 2004-08-31
The last revision prior to the SCOP 1.73 freeze date was dated 2004-09-28, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.208
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Androgen receptor
    Species: Pan troglodytes
    Gene: Ar, Nr3c4
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1t76a_
  • Chain 'B':
    Compound: WxxVW motif peptide
    Species: synthetic, synthetic
  • Heterogens: SO4, NA, DHT, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1t76A (A:)
gspgisgggggshiegyecqpiflnvleaiepgvvcaghdnnqpdsfaallsslnelger
qlvhvvkwakalpgfrnlhvddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvf
neyrmhksrmysqcvrmrhlsqefgwlqitpqeflcmkalllfsiipvdglknqkffdel
rmnyikeldriiackrknptscsrrfyqltklldsvqpiarelhqftfdllikshmvsvd
fpemmaeiisvqvpkilsgkvkpiyfhtq

    Sequence, based on observed residues (ATOM records): (download) 
    >1t76A (A:)
qpiflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlh
vddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrh
lsqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiackrknp
tscsrrfyqltklldsvqpiarelhqftfdllikshmvsvdfpemmaeiisvqvpkilsg
kvkpiyfht

  • Chain 'B':
    No sequence available.