PDB entry 1t69

View 1t69 on RCSB PDB site
Description: Crystal Structure of human HDAC8 complexed with SAHA
Class: hydrolase
Keywords: histone deacetylase, zinc hydrolase
Deposited on 2004-05-05, released 2004-07-27
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.91 Å
R-factor: 0.249
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone deacetylase 8
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9BY41 (Start-376)
      • conflict (30)
    Domains in SCOPe 2.06: d1t69a_
  • Heterogens: ZN, SHH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1t69A (A:)
meepeepadsgqslvpvyiyspeyvsmcdslakipkrasmvhslieayalhkqmrivkpk
vasmeematfhtdaylqhlqkvsqegdddhpdsieyglgydcpategifdyaaaiggati
taaqclidgmckvainwsggwhhakkdeasgfcylndavlgilrlrrkferilyvdldlh
hgdgvedafsftskvmtvslhkfspgffpgtgdvsdvglgkgryysvnvpiqdgiqdeky
yqicesvlkevyqafnpkavvlqlgadtiagdpmcsfnmtpvgigkclkyilqwqlatli
lggggynlantarcwtyltgvilgktlsseipdhefftaygpdyvleitpscrpdrneph
riqqilnyikgnlkhvv

    Sequence, based on observed residues (ATOM records): (download) 
    >1t69A (A:)
lvpvyiyspeyvsmcdslakipkrasmvhslieayalhkqmrivkpkvasmeematfhtd
aylqhlqkvsqpdsieyglgydcpategifdyaaaiggatitaaqclidgmckvainwsg
gwhhakkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedafsftskvmtvs
lhkfspgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyqafnpka
vvlqlgadtiagdpmcsfnmtpvgigkclkyilqwqlatlilggggynlantarcwtylt
gvilgktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnlkhvv