PDB entry 1t4f

View 1t4f on RCSB PDB site
Description: Structure of human MDM2 in complex with an optimized p53 peptide
Class: ligase
Keywords: MDM2-p53 peptide complex, p53-binding protein Mdm2 Oncoprotein Mdm2 Double minute 2 protein Hdm2
Deposited on 2004-04-29, released 2005-02-08
The last revision prior to the SCOP 1.73 freeze date was dated 2005-04-12, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.197
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'M':
    Compound: ubiquitin-protein ligase e3 mdm2
    Species: HOMO SAPIENS
    Gene: MDM2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1t4fm1
  • Chain 'P':
    Compound: optimized p53 peptide
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'M':
    Sequence, based on SEQRES records: (download)
    >1t4fM (M:)
    gsqipaseqetlvrpkplllkllksvgaqkdtytmkevlfylgqyimtkrlydekqqhiv
    ycsndllgdlfgvpsfsvkehrkiytmiyrnlvvvnqqessdsgtsvsen
    

    Sequence, based on observed residues (ATOM records): (download)
    >1t4fM (M:)
    eqetlvrpkplllkllksvgaqkdtytmkevlfylgqyimtkrlydekqqhivycsndll
    gdlfgvpsfsvkehrkiytmiyrnlvvv
    

  • Chain 'P':
    No sequence available.