PDB entry 1t45
View 1t45 on RCSB PDB site
Description: structural basis for the autoinhibition and sti-571 inhibition of c-kit tyrosine kinase
Class: transferase activator
Keywords: kinase, autoinhibition, transferase activator
Deposited on
2004-04-28, released
2004-06-15
The last revision prior to the SCOPe 2.07 freeze date was dated
2017-08-23, with a file datestamp of
2017-08-18.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Species: Homo sapiens [TaxId:9606]
Gene: KIT
Database cross-references and differences (RAF-indexed):
- Uniprot P10721 (0-146)
- GB NP_000213 (149-330)
Domains in SCOPe 2.07: d1t45a_ - Heterogens: HOH