PDB entry 1t44

View 1t44 on RCSB PDB site
Description: Structural basis of actin sequestration by thymosin-B4: Implications for arp2/3 activation
Class: structural protein
Keywords: structural protein
Deposited on 2004-04-28, released 2004-09-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-08-23, with a file datestamp of 2017-08-18.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Actin, alpha
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1t44a1, d1t44a2
  • Chain 'G':
    Compound: Chimera of Gelsolin domain 1 and C-Terminal domain of thymosin Beta-4
    Species: , [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1t44g_
  • Heterogens: CA, ATP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1t44A (A:)
    talvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqskrgil
    tlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimfe
    tfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrdl
    tdylmkiltergysfvttaereivrdikeklcyvaldfenemataassssleksyelpdg
    qvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggttm
    ypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkqeydea
    gpsivhrkcf
    

    Sequence, based on observed residues (ATOM records): (download)
    >1t44A (A:)
    talvcdngsglvkagfagddapravfpsivgrpdsyvgdeaqskrgiltlkypiehgiit
    nwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimfetfnvpamyvaiq
    avlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrdltdylmkilterg
    ysfvttaereivrdikeklcyvaldfenemataassssleksyelpdgqvitignerfrc
    petlfqpsfigmesagihettynsimkcdidirkdlyannvmsggttmypgiadrmqkei
    talapstmkikiiapperkysvwiggsilaslstfqqmwitkqeydeagpsivhrkcf
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >1t44G (G:)
    gshehpeflkagkepglqiwrvekfdlvpvptnlygdfftgdayvilktvqlrngnlqyd
    lhywlgnecsqdesgaaaiftvqlddylngravqhrevqgfesatflgyfksglkykkgg
    vasgfkhvetqeknplpsketieqekq
    

    Sequence, based on observed residues (ATOM records): (download)
    >1t44G (G:)
    ehpeflkagkepglqiwrvekfdlvpvptnlygdfftgdayvilktvqlrngnlqydlhy
    wlgnecsqdesgaaaiftvqlddylngravqhrevqgfesatflgyfksglkykkggvas
    gfkhvetqeknplpsketieqekq